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Artikel-Nr:
(BOSSBS-0417R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0417R-CY5.5
Lokale Artikelnummer::
BOSSBS-0417R-CY5.5
Beschreibung:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4890R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4890R-CY5.5
Lokale Artikelnummer::
BOSSBS-4890R-CY5.5
Beschreibung:
Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6647R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6647R-CY3
Lokale Artikelnummer::
BOSSBS-6647R-CY3
Beschreibung:
There are eight COG proteins (COG1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that COG1 is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5214R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5214R-CY5
Lokale Artikelnummer::
BOSSBS-5214R-CY5
Beschreibung:
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant, and recessive forms of nephrogenic diabetes insipidus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4208R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4208R-A680
Lokale Artikelnummer::
BOSSBS-4208R-A680
Beschreibung:
Cullin 1 may be involved in the degradation of positive cell cycle regulators (for example G1 cyclins in yeast). Human cullin 1 forms a complex with Skp1 and the F box protein Skp2, which is thought to play a role in the ubiquitination of G1 regulatory proteins, as its homolog does in yeast.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5804R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5804R-CY5
Lokale Artikelnummer::
BOSSBS-5804R-CY5
Beschreibung:
Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5105R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5105R-CY5
Lokale Artikelnummer::
BOSSBS-5105R-CY5
Beschreibung:
PRE7 is a subunit of the Yeast proteasome. The yeast proteasome seems to be composed of 14 different subunits which form a highly ordered ring-shaped structure. The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8329R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8329R-CY5
Lokale Artikelnummer::
BOSSBS-8329R-CY5
Beschreibung:
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3862R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3862R-A680
Lokale Artikelnummer::
BOSSBS-3862R-A680
Beschreibung:
SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3862R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3862R-A750
Lokale Artikelnummer::
BOSSBS-3862R-A750
Beschreibung:
SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8464R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8464R-CY5.5
Lokale Artikelnummer::
BOSSBS-8464R-CY5.5
Beschreibung:
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3451R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-A750
Lokale Artikelnummer::
BOSSBS-3451R-A750
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyses the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localised to chromsome 17 and the beta gene is localised to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10380R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10380R-A680
Lokale Artikelnummer::
BOSSBS-10380R-A680
Beschreibung:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple Signalling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12949R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12949R-A680
Lokale Artikelnummer::
BOSSBS-12949R-A680
Beschreibung:
CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation. In the endoplasmic reticulum (ER), CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, the major structural proteins of skin and bone. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterised by bone fragility and susceptibility to fractures. OI type 7 is a mild form of this disorder, while OI type 2B is a neonatal lethal condition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5036R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5036R-CY7
Lokale Artikelnummer::
BOSSBS-5036R-CY7
Beschreibung:
Apolipoprotein C-II (apoCII) is in found in chylomicrons (large lipoprotein particles absorbed from the gastrointestinal tract) and VLDL (large lipoproteins that are broken down to eventually form LDL). ApoCII activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8691R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8691R-CY3
Lokale Artikelnummer::
BOSSBS-8691R-CY3
Beschreibung:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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