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3,6-Difluorphthalsäureanhydrid
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3,6-Difluorphthalsäureanhydrid
Artikel-Nr:
(BOSSBS-13140R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13140R
Lokale Artikelnummer::
BOSSBS-13140R
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13140R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13140R-CY3
Lokale Artikelnummer::
BOSSBS-13140R-CY3
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13140R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13140R-CY5
Lokale Artikelnummer::
BOSSBS-13140R-CY5
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11607R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11607R-A647
Lokale Artikelnummer::
BOSSBS-11607R-A647
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC54 (leucine-rich repeat-containing protein 54), also known as tsukushin, TSKU or E2-induced gene 4 protein (E2IG4), is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments. Involved in extracellular secretion and intracellular transport, LRRC54 can be induced by 17-beta-estradiol. Containing nine LRR repeat and a cleavable signal peptide, the gene encoding LRRC54 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL245607-10G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
245607-10G
Lokale Artikelnummer::
SIAL245607-10G
Beschreibung:
3,4-Dichlorphenylisocyanat, Sigma-Aldrich®
VE:
1 * 10 g
Artikel-Nr:
(WITG3.668.005)
Lieferant:
WITEG LABORTECHNIK
Hersteller-Artikelnummer::
3.668.005
Lokale Artikelnummer::
WITG3.668.005
Beschreibung:
Borosilikatglas 3.3, mit hohlem Glasstopfen.
VE:
1 * 1 ST
Lieferant:
TOSOH Bioscience
Beschreibung:
These columns are designed for GFC of water soluble organic polymers, polysaccharides, oligosaccharides, DNA and RNA. They are based on a hydrophilic polymethacrylate matrix, which is stable from pH 2 to 12 and in aqueous eluents with up to 50% polar organic solvent.
Artikel-Nr:
(216-0271)
Lieferant:
RSG
Hersteller-Artikelnummer::
730.012
Lokale Artikelnummer::
RSGA730.012
Beschreibung:
Edelstahl, rostfrei, hochglänzend.
VE:
1 * 1 ST
Artikel-Nr:
(300-0618)
Lieferant:
Sampling Systems
Hersteller-Artikelnummer::
A100-20
Lokale Artikelnummer::
SAMPA100-20
Beschreibung:
Perfect for transferring small amounts of powder.
VE:
1 * 1 ST
Artikel-Nr:
(MOLE54413003-1G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
54413003-1G
Lokale Artikelnummer::
MOLE54413003-1G
Beschreibung:
n-Tridecyl-β-D-maltosid
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(214-0386)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
292040406
Lokale Artikelnummer::
SCOT292040406
Beschreibung:
Octagonal PE stoppers.
VE:
1 * 10 ST
Artikel-Nr:
(ABNOMAB15449)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB15449
Lokale Artikelnummer::
ABNOMAB15449
Beschreibung:
Mouse monoclonal antibody raised against native mouse H2-D1.
VE:
1 * 100 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
1,1'-Azobis(N,N-dimethylformamid), Sigma-Aldrich®
Artikel-Nr:
(SIAL410829-25ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
410829-25ML
Lokale Artikelnummer::
SIAL410829-25ML
Beschreibung:
9,10-Epoxy-1-decen, Sigma-Aldrich®
VE:
1 * 25 mL
Artikel-Nr:
(MOLEM63590011)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M63590011
Lokale Artikelnummer::
MOLEM63590011
Beschreibung:
2-Aminopyrimidin
VE:
1 * 500 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(CPSD8560409)
Lieferant:
CAPITAL SAFETY
Hersteller-Artikelnummer::
8560409
Lokale Artikelnummer::
CPSD8560409
Beschreibung:
This pole hoist attaches to a carabiner on the universal bracket to a suitable anchor point, allowing to work in any direction from any angle.
VE:
1 * 1 ST
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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