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Tetrabutylazanium+trifluoro(3-methoxyphenyl)boranuide
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Tetrabutylazanium+trifluoro(3-methoxyphenyl)boranuide
Artikel-Nr:
(PRSI33-233)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-233
Lokale Artikelnummer::
PRSI33-233
Beschreibung:
Recognises a protein of 47-55 kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterised by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(BOSSBS-12330R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12330R-A488
Lokale Artikelnummer::
BOSSBS-12330R-A488
Beschreibung:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å and IFN-∫, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12330R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12330R-A555
Lokale Artikelnummer::
BOSSBS-12330R-A555
Beschreibung:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å and IFN-∫, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15350R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15350R-A750
Lokale Artikelnummer::
BOSSBS-15350R-A750
Beschreibung:
C9orf96, also known as Protein kinase-like protein SgK071, is a 680 amino acid protein that belongs to the Ser/Thr protein kinase family of the protein kinase superfamily. There are three isoforms of C9orf96 that are produced as a result of alternative splicing events. The gene encoding C9orf96 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Lieferant:
MACHEREY-NAGEL
Beschreibung:
Septen, Silikon virginal/PTFE farblos, Härte: 45° shore A, Stärke: 3,2 mm, Ø: 22 mm
Lieferant:
Sigma-Aldrich
Beschreibung:
(S)-(-)-1,1'-Bi-2-naphthol, Sigma-Aldrich®
Artikel-Nr:
(PRSI76-050)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-050
Lokale Artikelnummer::
PRSI76-050
Beschreibung:
The 3H5 monoclonal antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction/co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
The 3H5 antibody blocks the binding of CD80 to its ligands.
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI76-049)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-049
Lokale Artikelnummer::
PRSI76-049
Beschreibung:
The 3H5 monoclonal antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction/co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
The 3H5 antibody blocks the binding of CD80 to its ligands.
VE:
1 * 0,1 mg
New Product
Lieferant:
Sigma-Aldrich
Beschreibung:
Diethylenglycol, Sigma-Aldrich®
Lieferant:
MARIENFELD
Beschreibung:
Hergestellt aus chemisch beständigem Borosilikatglas D 263™ M, hydrolytische Klasse I
Artikel-Nr:
(PROOCIL-PCB-95)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-95
Lokale Artikelnummer::
PROOCIL-PCB-95
Beschreibung:
Organic Standard, 2,2',3,5',6-Pentachlorbiphenyl (PCB Nr. 95) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-101)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-101
Lokale Artikelnummer::
PROOCIL-PCB-101
Beschreibung:
Organic Standard, 2,2',4,5,5'-Pentachlorbiphenyl (PCB Nr. 101) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-44)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-44
Lokale Artikelnummer::
PROOCIL-PCB-44
Beschreibung:
Organic Standard, 2,2',3,5'-Tetrachlorbiphenyl (PCB Nr. 44) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-43)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-43
Lokale Artikelnummer::
PROOCIL-PCB-43
Beschreibung:
Organic Standard, 2,2',3,5-Tetrachlorbiphenyl (PCB Nr. 43) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PROOCIL-PCB-149-CS)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-149-CS
Lokale Artikelnummer::
PROOCIL-PCB-149-CS
Beschreibung:
Organic Standard, 2,2',3,4',5',6-Hexachlorbiphenyl (PCB Nr. 149) 100 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1,2 mL
Artikel-Nr:
(PROOCIL-PCB-141)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-141
Lokale Artikelnummer::
PROOCIL-PCB-141
Beschreibung:
Organic Standard, 2,2',3,4,5,5'-Hexachlorbiphenyl (PCB Nr. 141) 35 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 1 mL
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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