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5-(tert-Butyldimethylsilyloxy)-2-fluorphenylboronsäure
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5-(tert-Butyldimethylsilyloxy)-2-fluorphenylboronsäure
Artikel-Nr:
(BOSSBS-8165R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8165R-A488
Lokale Artikelnummer::
BOSSBS-8165R-A488
Beschreibung:
Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12143R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12143R-CY7
Lokale Artikelnummer::
BOSSBS-12143R-CY7
Beschreibung:
Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters. By way of this control of actin dynamics, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling. Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity. May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8998R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8998R-A750
Lokale Artikelnummer::
BOSSBS-8998R-A750
Beschreibung:
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13067R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13067R-FITC
Lokale Artikelnummer::
BOSSBS-13067R-FITC
Beschreibung:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR911336-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR911336-100G
Lokale Artikelnummer::
APOSOR911336-100G
Beschreibung:
Ethyl-2-ethoxybenzoat 95%
VE:
1 * 100 g
Lieferant:
Thermo Scientific
Beschreibung:
Ethyl-4-nitrobenzoat 99%
Lieferant:
THERMO FISHER DIAGNOSTICS
Beschreibung:
ReadyBags™ are designed for use in food testing by laboratories with large numbers of samples requiring large volumes of broth media or diluent. Each ReadyBag™ contains 3 liters and is intended for use with an automatic dispenser. The ReadyBag™ is connected to tubing for standard laboratory equipment, such as gravimetric diluters or peristaltic pumps, by means of a connector. Connectors are available in two formats: autoclavable, re-usable stainless steel connectors or sterile, plastic, single-use connectors.
Artikel-Nr:
(BOSSBS-5691R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5691R-CY5.5
Lokale Artikelnummer::
BOSSBS-5691R-CY5.5
Beschreibung:
A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10178R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10178R-CY3
Lokale Artikelnummer::
BOSSBS-10178R-CY3
Beschreibung:
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR470054-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR470054-5G
Lokale Artikelnummer::
APOSOR470054-5G
Beschreibung:
Ethyl 2-(Methylsulphonyl)nicotinate
VE:
1 * 5 g
Artikel-Nr:
(APOSPC0995-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC0995-100G
Lokale Artikelnummer::
APOSPC0995-100G
Beschreibung:
Ethyl-2-fluoroacetoacetate 97%
VE:
1 * 100 g
Artikel-Nr:
(42582-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
42582-1G
Lokale Artikelnummer::
SUPL42582-1G
Beschreibung:
Organic Standard, Ethyl 4-(dimethylamino)benzoate
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-2,6-dichlorbenzoat
Artikel-Nr:
(BOSSBS-5899R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5899R-A750
Lokale Artikelnummer::
BOSSBS-5899R-A750
Beschreibung:
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-1-naphthaleneacetate 98%
Artikel-Nr:
(91224-1ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
91224-1ML
Lokale Artikelnummer::
SUPL91224-1ML
Beschreibung:
Organic Standard, Ethyl phenylacetate
VE:
1 * 1 mL
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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