Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
Artikel-Nr:
(APOSOR1008554-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1008554-25G
Lokale Artikelnummer::
APOSOR1008554-25G
Beschreibung:
(R)-Rel-3-((R)-1-Benzylpiperidin-3-Yl) 5-Methyl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate Hydrochloride 2 5g pack 1 * 25 g
VE:
1 * 25 g
New Product
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
HEPES (2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethansulfonsäure) freie Säure ≥99% (durch Alkalimetrie), Molekularbiologische Qualität, Millipore®
Artikel-Nr:
(APOSOR1008357-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1008357-100G
Lokale Artikelnummer::
APOSOR1008357-100G
Beschreibung:
(E)-Diethyl4-(2-(3-(Tert-Butoxy)-3-Oxoprop-1-En-1-Yl)Phenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate 100g pack 1 * 100 g
VE:
1 * 100 g
New Product
Artikel-Nr:
(APOSOR1008357-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1008357-25G
Lokale Artikelnummer::
APOSOR1008357-25G
Beschreibung:
(E)-Diethyl4-(2-(3-(Tert-Butoxy)-3-Oxoprop-1-En-1-Yl)Phenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate 25g pack 1 * 25 g
VE:
1 * 25 g
New Product
Artikel-Nr:
(APOSOR1010981-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1010981-5G
Lokale Artikelnummer::
APOSOR1010981-5G
Beschreibung:
3-Ethyl 5-Methyl 4-(2,3-Dichlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate 5g pack 1 * 5 g
VE:
1 * 5 g
New Product
Artikel-Nr:
(APOSOR90241-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR90241-1G
Lokale Artikelnummer::
APOSOR90241-1G
Beschreibung:
Dimethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 1g pack 1 * 1 g
VE:
1 * 1 g
New Product
Artikel-Nr:
(APOSOR1010981-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1010981-25G
Lokale Artikelnummer::
APOSOR1010981-25G
Beschreibung:
3-Ethyl 5-Methyl 4-(2,3-Dichlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate 25g pack 1 * 25 g
VE:
1 * 25 g
New Product
Artikel-Nr:
(APOSOR90241-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR90241-5G
Lokale Artikelnummer::
APOSOR90241-5G
Beschreibung:
Dimethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 5g pack 1 * 5 g
VE:
1 * 5 g
New Product
Lieferant:
Corning Life Science
Beschreibung:
HEPES (N-2-hydroxyethylpiperazine-N’-2-ethanesulphonic acid) provides an alternative to the use of bicarbonate for buffering because it does not require elevated levels of CO<sub>2</sub>
Lieferant:
MP Biomedicals
Beschreibung:
HEPES is a zwitterionic organic chemical buffering agent.
HEPES is widely used in many biochemical reactions and as a buffering agent in some cell culture media.
Artikel-Nr:
(APOSOR1010981-500G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1010981-500G
Lokale Artikelnummer::
APOSOR1010981-500G
Beschreibung:
3-Ethyl 5-Methyl 4-(2,3-Dichlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate 500g pack 1 * 500 g
VE:
1 * 500 g
New Product
Artikel-Nr:
(APOSOR1010981-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1010981-100G
Lokale Artikelnummer::
APOSOR1010981-100G
Beschreibung:
3-Ethyl 5-Methyl 4-(2,3-Dichlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate 100g pack 1 * 100 g
VE:
1 * 100 g
New Product
Artikel-Nr:
(PRSI27-948)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-948
Lokale Artikelnummer::
PRSI27-948
Beschreibung:
The CD233 gene is located on chromosome 17q21-q22 and is part of the anion exchanger (AE) family. CD233 is expressed in the erythrocyte plasma membrane where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The cytoplasmic tail at the extreme C-terminus of the membrane domain binds carbonic anhydrase II. CD233 associates with the red cell membrane protein glycophorin A and this association promotes the correct folding and translocation of CD233. CD233 is predominantly dimeric but forms tetramers in the presence of ankyrin. Many CD233 mutations are known in man and these mutations can lead to two types of disease; destabilization of red cell membrane leading to hereditary spherocytosis, and defective kidney acid secretion leading to distal renal tubular acidosis. Other CD233 mutations that do not give rise to disease result in novel blood group antigens, which form the Diego blood group system. Southeast Asian ovalocytosis (SAO, Melanesian ovalocytosis) results from the heterozygous presence of a deletion in the CD233 protein and is common in areas where Plasmodium falciparum malaria is endemic. One CD233 null human is known also with very severe anemia and nephrocalcinosis [PROW].
VE:
1 * 50 µG
Lieferant:
MP Biomedicals
Beschreibung:
3-(4,5-Dimethylthiazolyl-2)-2,5-Diphenyl Tetrazolium Bromide(MTT) is an histochemical/cytochemical reagent. It is converted to water-insoluble MTT-formazan of dark blue color by mitochondrial dehydrogenases of living cells, thus used for measurement of cell division.
Lieferant:
MP Biomedicals
Beschreibung:
Storage: Store at Room Temperature (15-30 °C)
Sodium chloride is a commonly used chemical which is found widely in nature. It is considered to be an essential nutrient. Excess amounts of sodium chloride can destroy electrolyte balance and cause death in most animals, including humans. Sodium chloride is used in a wide variety of biochemical applications, including intravenous fluids (normal saline is 0.9% w/v in water), density gradients, a diluent to increase ionic strength in buffers or culture media and in salt-out procedures in the isolation of DNA. It has also been used in high concentrations for preservation of foods since bacteria cannot grow in high salt conditions. Sodium chloride is widely used in protein crystallization.
Artikel-Nr:
(BOSSBS-7599R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7599R-A680
Lokale Artikelnummer::
BOSSBS-7599R-A680
Beschreibung:
STK3: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation. Phosphorylates NKX2-1 (By similarity). Phosphorylates NEK2 and plays a role in centrosome disjunction by regulating the localization of NEK2 to centrosome, and its ability to phosphorylate CROCC and CEP250. In conjunction with SAV1, activates the transcriptional activity of ESR1 through the modulation of its phosphorylation. Positively regulates RAF1 activation via suppression of the inhibitory phosphorylation of RAF1 on 'Ser-259'. Phosphorylates MOBKL1A and RASSF2. Phosphorylates MOBKL1B on 'Thr-74'. Acts cooperatively with MOBKL1B to activate STK38.
STK4: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation (By similarity). Phosphorylates 'Ser-14' of histone H2B (H2BS14ph) during apoptosis. Phosphorylates FOXO3 upon oxidative stress, which results in its nuclear translocation and cell death initiation. Phosphorylates MOBKL1A, MOBKL1B and RASSF2. Phosphorylates TNNI3 (cardiac Tn-I) and alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T). Phosphorylates FOXO1 on 'Ser-212' and regulates its activation and stimulates transcription of PMAIP1 in a FOXO1-dependent manner. Phosphorylates SIRT1 and inhibits SIRT1-mediated p53/TP53 deacetylation, thereby promoting p53/TP53 dependent transcription and apoptosis upon DNA damage. Acts as an inhibitor of PKB/AKT1. Phosphorylates AR on 'Ser-650' and suppresses its activity by intersecting with PKB/AKT1 signaling and antagonizing formation of AR-chromatin complexes.
VE:
1 * 100 µl
Preis auf Anfrage
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