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Artikel-Nr:
(PRSI28-240)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-240
Lokale Artikelnummer::
PRSI28-240
Beschreibung:
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.
VE:
1 * 100 µG
Artikel-Nr:
(SIAL25510-500G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
25510-500G
Lokale Artikelnummer::
SIAL25510-500G
Beschreibung:
di-Kalium-L(+)-tartrat Hemihydrat, Sigma-Aldrich®
VE:
1 * 500 g
Artikel-Nr:
(PROORTCCOND147-500)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
RTCCOND147-500
Lokale Artikelnummer::
PROORTCCOND147-500
Beschreibung:
Conductivity standard, 147 µS/cm
VE:
1 * 500 mL
Artikel-Nr:
(APOSPC105414-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC105414-5G
Lokale Artikelnummer::
APOSPC105414-5G
Beschreibung:
Potassium Trifluoro(5-Formylfuran-2-Yl)Borate 5g pack 1 * 5 g
VE:
1 * 5 g
New Product
Lieferant:
HORIBA
Beschreibung:
Standardlösung, Kaliumion (2000 ppm) Y041H, in Flasche (14 ml), für B-731, Für: Ion selective meter, LAQUAtwin
Artikel-Nr:
(ROCK612-401-E15)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
612-401-E15
Lokale Artikelnummer::
ROCK612-401-E15
Beschreibung:
Anti-Potassium Chloride Cotransporter (KCC2) Antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 135 kDa in size.
VE:
1 * 100 µl
Artikel-Nr:
(APOSPC105414-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC105414-1G
Lokale Artikelnummer::
APOSPC105414-1G
Beschreibung:
Potassium Trifluoro(5-Formylfuran-2-Yl)Borate 1g pack 1 * 1 g
VE:
1 * 1 g
New Product
Artikel-Nr:
(BOSSBS-6252R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6252R-CY5.5
Lokale Artikelnummer::
BOSSBS-6252R-CY5.5
Beschreibung:
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI28-276)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-276
Lokale Artikelnummer::
PRSI28-276
Beschreibung:
KCNK13 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming domains. The product of this gene is an open channel that can be stimulated by arachidonic acid.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-6252R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6252R-A488
Lokale Artikelnummer::
BOSSBS-6252R-A488
Beschreibung:
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6252R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6252R-FITC
Lokale Artikelnummer::
BOSSBS-6252R-FITC
Beschreibung:
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6252R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6252R-A750
Lokale Artikelnummer::
BOSSBS-6252R-A750
Beschreibung:
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6252R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6252R-HRP
Lokale Artikelnummer::
BOSSBS-6252R-HRP
Beschreibung:
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI26-222)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-222
Lokale Artikelnummer::
PRSI26-222
Beschreibung:
TMEM38B is a monovalent cation channel required for maintenance of rapid intracellular calcium release. It may act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
VE:
1 * 50 µG
Artikel-Nr:
(MANA934220)
Lieferant:
MACHEREY-NAGEL
Hersteller-Artikelnummer::
934220
Lokale Artikelnummer::
MANA934220
Beschreibung:
This portable laboratory case contains all reagents, instruments and accessories required for the preparation of soil extracts and the subsequent analysis of phosphate (P), potassium (K), ammonium, nitrate, nitrite (N), soil structure and pH.
VE:
1 * 1 ST
Lieferant:
Hach
Beschreibung:
Konzentration: 0,001 mol/l KCl), 147 µS/cm
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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