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1-Boc-3-indolboronsäurepinakolester
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1-Boc-3-indolboronsäurepinakolester
Lieferant:
Biotium
Beschreibung:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Lieferant:
Biotium
Beschreibung:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Artikel-Nr:
(BOSSBS-11621R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11621R
Lokale Artikelnummer::
BOSSBS-11621R
Beschreibung:
The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Fmoc-N-Me-Phe-OH 97%
Artikel-Nr:
(BOSSBS-6127R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6127R-CY7
Lokale Artikelnummer::
BOSSBS-6127R-CY7
Beschreibung:
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), the primer for reverse transcription initiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0819R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0819R-CY5.5
Lokale Artikelnummer::
BOSSBS-0819R-CY5.5
Beschreibung:
Tyrosinase is the key enzyme for melanin,synthesis in mammalian melanocytes and has been considered to be a unique marker for the study of melanocyte differentiation. A cDNA library was constructed from poly(A)+ mRNA from mouse melanocytes and screened using anti- tyrosinase antiserum and oligonucleotide probes corresponding to amino acid sequence of tyrosinase. sequencing of some cDNA clones positive in these screenings gave a nucleotide sequence of 1838 nucleotides including a open reading frame of 1344 nucleotides that was found to correspond exactly to the amino acid sequence of the cyanogen bromide fragments of tyrosinase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0819R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0819R-CY7
Lokale Artikelnummer::
BOSSBS-0819R-CY7
Beschreibung:
Tyrosinase is the key enzyme for melanin,synthesis in mammalian melanocytes and has been considered to be a unique marker for the study of melanocyte differentiation. A cDNA library was constructed from poly(A)+ mRNA from mouse melanocytes and screened using anti- tyrosinase antiserum and oligonucleotide probes corresponding to amino acid sequence of tyrosinase. sequencing of some cDNA clones positive in these screenings gave a nucleotide sequence of 1838 nucleotides including a open reading frame of 1344 nucleotides that was found to correspond exactly to the amino acid sequence of the cyanogen bromide fragments of tyrosinase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6841R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6841R-A555
Lokale Artikelnummer::
BOSSBS-6841R-A555
Beschreibung:
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6841R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6841R-A488
Lokale Artikelnummer::
BOSSBS-6841R-A488
Beschreibung:
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11061R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11061R-A647
Lokale Artikelnummer::
BOSSBS-11061R-A647
Beschreibung:
OLFM3 is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11213R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11213R-A680
Lokale Artikelnummer::
BOSSBS-11213R-A680
Beschreibung:
The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11213R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11213R-A750
Lokale Artikelnummer::
BOSSBS-11213R-A750
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localises to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6613R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6613R-A647
Lokale Artikelnummer::
BOSSBS-6613R-A647
Beschreibung:
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11061R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11061R-CY3
Lokale Artikelnummer::
BOSSBS-11061R-CY3
Beschreibung:
OLFM3 is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13618R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13618R-FITC
Lokale Artikelnummer::
BOSSBS-13618R-FITC
Beschreibung:
A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12323R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12323R-A750
Lokale Artikelnummer::
BOSSBS-12323R-A750
Beschreibung:
Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells. CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch. The human protein contains 1225 amino acid residues and shares significant homology with the domain structures of the rat protein.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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