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Ethyl+3-(4-Isobutylphenyl)acrylate
Artikel-Nr:
(PRSIXPS-2019)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XPS-2019
Lokale Artikelnummer::
PRSIXPS-2019
Beschreibung:
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity.
VE:
1 * 15 µG
Artikel-Nr:
(PRSI28-275)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-275
Lokale Artikelnummer::
PRSI28-275
Beschreibung:
GABRE belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIXP-5115)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5115
Lokale Artikelnummer::
PRSIXP-5115
Beschreibung:
Ciliary neurotrophic factor (CNTF) is expressed in glial cells within the central and peripheral nervous systems. CNTF stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types such as sensory, sympathetic, ciliary and motor neurons. CNTF itself lacks a classical signal peptide sequence of a secreted protein, but is thought to convey its cytoprotective effects after release from adult glial cells by some mechanism induced by injury.
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXPS-1020)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XPS-1020
Lokale Artikelnummer::
PRSIXPS-1020
Beschreibung:
The three Mitogen-Activated Protein Kinases (MAPKs) are evolutionarily conserved protein kinases that control a vast array of cellular processes. p38 MAPK is one these kinases and it is activated by both inflammatory cytokines and by stress. The p38 MAPK is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI29-021)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-021
Lokale Artikelnummer::
PRSI29-021
Beschreibung:
POGZ appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid systemThe protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-671)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-671
Lokale Artikelnummer::
PRSI29-671
Beschreibung:
CHGA is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. Its gene's product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-560)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-560
Lokale Artikelnummer::
PRSI25-560
Beschreibung:
MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-108)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-108
Lokale Artikelnummer::
PRSI25-108
Beschreibung:
POGZ appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system.The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
VE:
1 * 50 µG
Lieferant:
VACUUBRAND
Beschreibung:
The three-stage VARIO-SP® diaphragm pumps, with its variable speed drive system, attains significantly higher pumping speed and a better ultimate vacuum than the corresponding fixed speed pump. The brushless motor (maintenance-free) enables easy integration of the pump into other equipment, and operation independent of line voltage. The motor speed is either fixed or can be adjusted externally via electronic control signals for adaptation to process requirements.
Artikel-Nr:
(PRSI92-217)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-217
Lokale Artikelnummer::
PRSI92-217
Beschreibung:
tumour Necrosis Factor- alpha (TNF- alpha) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF- alpha while cells that express CD8 secrete little or no TNF- alpha. Synthesis of TNF- alpha can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumour activity of TNF- alpha has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF- alpha mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF- alpha that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumour activity and reduced systemic toxicity in mice compared with murine TNF- alpha, which binds to both murine TNF receptors. Based on these results, many TNF- alpha mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumour cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF- alpha High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7091)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7091
Lokale Artikelnummer::
PRSI7091
Beschreibung:
NGN2 Antibody: Neurogenin-2 (NGN2) is a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. NGN2 is thought to work with Nurr1 to play a role in the differentiation and survival of midbrain dopaminergic neurons. It has also been suggested for use in human embryonic neural progenitors as a graft for spinal cord injuries
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6405)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6405
Lokale Artikelnummer::
PRSI6405
Beschreibung:
SPRYD3 Antibody: The SPRY domain-containing protein 3 (SPRYD3) is a member of a family of proteins whose sole common characteristic is the presence of a SPRY domain. SPRY domains are structural domains that were first described in the fungal Dictyostelium discoideum tyrosine kinase spore lysis A. In most systems SPRY domains provide binding sites for regulatory proteins or intramolecular binding sites that maintain the structural integrity of a protein. Little is known of the function of the SPRYD3 protein.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-083)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-083
Lokale Artikelnummer::
PRSI33-083
Beschreibung:
This antibody recognises a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. antibody to CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. CD5 antibody detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, antibody to CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). CD5 antibody does not react with granulocytes or monocytes.
VE:
1 * 100 µG
Lieferant:
PERKIN ELMER GC INSTRUMENTS
Beschreibung:
These electrodeless discharge lamps are preferred for certain volatile elements. They offer better precision and lower detection limits for analyses that are 'noisy' due to weak hollow cathode emission. PerkinElmer system 2 EDLs consist of the element or a salt of the element sealed in a quartz bulb containing an inert gas atmosphere. When an RF field of sufficient power is applied, the inert gas is ionised and the coupled energy vaporizes the element and excites the atoms inside the bulb, resulting in the emission of the characteristic spectrum.
Artikel-Nr:
(PRSIXP-5114)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5114
Lokale Artikelnummer::
PRSIXP-5114
Beschreibung:
Ciliary neurotrophic factor (CNTF) is expressed in glial cells within the central and peripheral nervous systems. CNTF stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types such as sensory, sympathetic, ciliary and motor neurons. CNTF itself lacks a classical signal peptide sequence of a secreted protein, but is thought to convey its cytoprotective effects after release from adult glial cells by some mechanism induced by injury.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-11648R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11648R-A680
Lokale Artikelnummer::
BOSSBS-11648R-A680
Beschreibung:
BSMAP is a 342 amino acid type-I membrane glycoprotein that localizes to organelle membranes and belongs to the TMEM59 family. Expressed at high levels in brain tissue, BSMAP is thought to play a role in brain function and central nervous system activity. The gene encoding BSMAP maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1400 genes and is recognised for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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