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N-Fmoc-N-benzyl-glycine
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N-Fmoc-N-benzyl-glycine
Artikel-Nr:
(BOSSBS-11929R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11929R-HRP
Lokale Artikelnummer::
BOSSBS-11929R-HRP
Beschreibung:
Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate with specificities to collagens. The development of type specific is dependent on NON DENATURED three dimensional epitopes. This may result in diminished reactivity of some with denatured collagen or formalin fixed, paraffin embedded tissues. Type II collagen is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Collagen type II is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(SIALG5418-100ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
G5418-100ML
Lokale Artikelnummer::
SIALG5418-100ML
Beschreibung:
Zur Anwendung in der enzymatischen Bestimmung von Lactat mittels Lactatdehydrogenase.
VE:
1 * 100 mL
Artikel-Nr:
(BOSSBS-2970R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2970R-CY5
Lokale Artikelnummer::
BOSSBS-2970R-CY5
Beschreibung:
The survival and development of central neurons require the supply of trophic factors by glial cells. The trophic actions of glial cells on Purkinje neurons are mediated by L-serine and glycine, which are glia-derived trophic factors synthesized by 3PGDH (1). 3PGDH protein is 544 amino acids in length. Two distinct mRNA transcripts that encode for 3PGDH protein in normal human tissues are dominant 2.1 kb mRNA, which is highly expressed in prostate, testis, ovary, brain, liver, kidney, and pancreas, and weakly expressed in thymus, colon, and heart, and 710 bp mRNA, which is highly expressed in heart and skeletal muscle (2). 3PGDH is regulated at the transcriptional level depending on tissue specificity and cellular proliferative status (2). 3PGDH protein is also highly expressed in adult and fetal brain tissues (3). 3PGDH protein plays an important role in the metabolism, development, and function of the central nervous system (3) and its deficiency is a treatable congential error (4-5) that impairs L-serine biosynthesis which is characterized by congenital microcephaly, psychomotor retardation, and seizures (3).
VE:
1 * 100 µl
Artikel-Nr:
(SIALT7777-1L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
T7777-1L
Lokale Artikelnummer::
SIALT7777-1L
Beschreibung:
Laufpuffer, TRIS-Glycin-SDS-Puffer-Lösung 10fach konzentriert (TGS-Puffer)
VE:
1 * 1 L
Artikel-Nr:
(BOSSBS-9095R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9095R-HRP
Lokale Artikelnummer::
BOSSBS-9095R-HRP
Beschreibung:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon.
Artikel-Nr:
(BOSSBS-9095R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9095R-A488
Lokale Artikelnummer::
BOSSBS-9095R-A488
Beschreibung:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9095R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9095R-A750
Lokale Artikelnummer::
BOSSBS-9095R-A750
Beschreibung:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localises to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
VE:
1 * 100 µl
Artikel-Nr:
(733-1629)
Lieferant:
LONZA
Hersteller-Artikelnummer::
50879
Lokale Artikelnummer::
LONZ50879
Beschreibung:
AccuGENE™ electrophoresis buffers are ready-to-use solutions ideal for a wide range of molecular biology applications.
VE:
1 * 1 L
Artikel-Nr:
(HONCR1747-25MG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1747-25MG
Lokale Artikelnummer::
HONCR1747-25MG
Beschreibung:
Organic Standard, Aminoethoxyvinyl glycine hydrochloride, Packung: Glass bottle
VE:
1 * 25 mg
Artikel-Nr:
(J62215.06)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J62215.06
Lokale Artikelnummer::
ALFAJ62215.06
Beschreibung:
Nicotinoyl-Glycin ≥98%
VE:
1 * 5 g
Artikel-Nr:
(SIAL93321-1L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
93321-1L
Lokale Artikelnummer::
SIAL93321-1L
Beschreibung:
Elektrophorese-Puffer, Transfer buffer, TRIS-Glycin-Puffer-Lösung 10fach konzentriert (TG-Puffer)
VE:
1 * 1 L
Artikel-Nr:
(SIAL93015-10L-F)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
93015-10L-F
Lokale Artikelnummer::
SIAL93015-10L-F
Beschreibung:
Elektrophorese-Puffer, Transfer buffer, TRIS-Glycin-Puffer-Lösung 10fach konzentriert (TG-Puffer)
VE:
1 * 10 L
Artikel-Nr:
(USBI034298)
Lieferant:
US Biological
Hersteller-Artikelnummer::
034298
Lokale Artikelnummer::
USBI034298
Beschreibung:
Anti-CSRP3 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(A1415.1000)
Lieferant:
PanReac AppliChem
Hersteller-Artikelnummer::
A1415.1000
Lokale Artikelnummer::
APLIA1415.1000
Beschreibung:
Laufpuffer, TRIS-Glycin-SDS-Puffer-Lösung 10fach konzentriert (TGS-Puffer) pH 8,3
VE:
1 * 1 L
Artikel-Nr:
(BOSSBS-9851R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9851R-A750
Lokale Artikelnummer::
BOSSBS-9851R-A750
Beschreibung:
The formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs. This process is mediated by the survival of motor neuron (SMN) protein, and is enhanced by modification of specific arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs). sDMA modification of Sm proteins is catalysed by the methylosome, a complex comprised of the type II methyltransferase PRMT5 (also designated Jak-binding protein 1, JBP1), pICln, and two novel factors. PRMT5 binds the Sm proteins via their arginine- and glycine-rich (RG) domains, while pICln binds the Sm domains. pICln also acts as an inhibitor of SnRNP assembly by preventing specific interactions between Sm proteins required for the formation of the Sm core. pICln is a highly conserved, ubiquitously expressed protein that localizes primarily to the cytoplasm, and may play a role as a swelling-activated anion channel or a channel regulator in addition to its function in the methylosome. The gene encoding human pICln maps to chromosome 11q14.1.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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