PathoGreen\u2122+Histofluorescent+Stain
Artikel-Nr:
(OHAU30770915)
Lieferant:
OHAUS
Hersteller-Artikelnummer::
30770915
Lokale Artikelnummer::
OHAU30770915
Beschreibung:
Endeavor™ Light Duty Shakers are available in 3 models: 3 and 20 mm orbit, or dedicated microplate model. All models can be used in incubators and cold rooms. Stable, accurate, long-term shaking is ensured with the triple eccentric drive and maintenance-free brushless DC motor. Integrated overload and unbalanced detection to protect samples.
VE:
1 * 1 Pack.
New Product
Artikel-Nr:
(STMC60072PS)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
60072PS
Lokale Artikelnummer::
STMC60072PS
Beschreibung:
Mouse monoclonal IgG2b, kappa isotype control antibody, PerCP-Cy5.5-conjugated.
VE:
1 * 100 µG
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Artikel-Nr:
(PRSI33-450)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-450
Lokale Artikelnummer::
PRSI33-450
Beschreibung:
Recognises a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
VE:
1 * 100 µG
Artikel-Nr:
(STMC60070)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
60070
Lokale Artikelnummer::
STMC60070
Beschreibung:
Mouse monoclonal IgG1, kappa isotype control antibody, unconjugated.
VE:
1 * 500 µG
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Lieferant:
IMMUNOLOGIC
Beschreibung:
Lu-5 reacts with an epitope which is common to all cytokeratins respectively with a cytokeratin-associated protein. The antigen recognized by anti-cytokeratin pan is present in all types of epithelia. It recognizes most subtypes of cytokeratins in cryofixed and paraffin sections and is ideally suited as a first order pan-epithelial marker. The epitope recognized by Lu-5 is a formalin-resistant marker of great value in tumour diagnosis, located on the surface of cytokeratin filaments. The epitope is present in most cytokeratin polypeptides of both the acidic (type I) and basic (type II) subfamily but does not occur in other cytoskeletal proteins. The epithelial specificity and the broad tissue and species crossreactivity provide an excellent probe for the differential diagnosis of epithelial versus mesenchymal tumours, large cell lymphomas and neural tumours.
Artikel-Nr:
(STMC60073AD)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
60073AD
Lokale Artikelnummer::
STMC60073AD
Beschreibung:
Mouse monoclonal IgG3, kappa isotype control antibody, Alexa Fluor® 488-conjugated.
VE:
1 * 100 µG
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Artikel-Nr:
(BSENR-183-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-183-50
Lokale Artikelnummer::
BSENR-183-50
Beschreibung:
LRRK2 is a member of the leucine-rich repeat kinase family. Its role is yet unknown but it may play a role in the phoshorylation of proteins central to parkinson diseases. LRRK2 contains an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain and a WD40 domain. LRRK2 is present in the cytoplasm but also associates with the mitochondrial outer membrane. Defects in LRRK2 are the cause of Parkinson disease 8 (PARK8). Parkinson disease is characterised by bradykinesia, resting tremor, muscular rigidity and postural instability, as well as by a clinically significant response to treatment with levodopa. The pathology involves the loss of dopaminergic neurons in the substantia nigra and the presence of Lewy bodies (intraneuronal accumulations of aggregated proteins), in surviving neurons in various areas of the brain. PARK8 is an autosomal-dominant late-onset parkinsonism, characterized by onset from 50 to 65 years, with slow progression and relatively benign course.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI34-112)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-112
Lokale Artikelnummer::
PRSI34-112
Beschreibung:
This mAb recognises a protein of ~50 kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
VE:
1 * 100 µG
Lieferant:
Portwest Clothing
Beschreibung:
These traffic jackets are designed to be worn in foul weather conditions, and offers excellent waterproof protection.
Artikel-Nr:
(PRSI33-432)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-432
Lokale Artikelnummer::
PRSI33-432
Beschreibung:
This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
VE:
1 * 100 µG
Lieferant:
Tonbo Biosciences
Beschreibung:
The UCHT1 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognise antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.
Artikel-Nr:
(BSENR-1751-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1751-50
Lokale Artikelnummer::
BSENR-1751-50
Beschreibung:
This antibody is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling.
VE:
1 * 50 µG
Lieferant:
Tonbo Biosciences
Beschreibung:
The UCHT1 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognise antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.
Artikel-Nr:
(PRSI33-446)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-446
Lokale Artikelnummer::
PRSI33-446
Beschreibung:
The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-460)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-460
Lokale Artikelnummer::
PRSI33-460
Beschreibung:
Recognises a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI34-189)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-189
Lokale Artikelnummer::
PRSI34-189
Beschreibung:
Recognises a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes. Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85 to 95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
VE:
1 * 100 µG
Preis auf Anfrage
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