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Plant+Learning+Activities
Artikel-Nr:
(201464-25G)
Lieferant:
SIGMA ALDRICH MICROSCOPY
Hersteller-Artikelnummer::
201464-25G
Lokale Artikelnummer::
SIAM201464-25G
Beschreibung:
Variamine Blue RT Salt has been used as a dye in ultraviolet-visible spectrophotometric method based-uricase enzyme for the detection of uric acid in normal urine. It is also used in combination with naphthol AS-MX phosphate-variam to determine the cytochemical visualization of alkaline phosphatase activity.
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-2767R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2767R
Lokale Artikelnummer::
BOSSBS-2767R
Beschreibung:
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3150R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3150R
Lokale Artikelnummer::
BOSSBS-3150R
Beschreibung:
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5997R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5997R-CY5
Lokale Artikelnummer::
BOSSBS-5997R-CY5
Beschreibung:
Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0828R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0828R-CY3
Lokale Artikelnummer::
BOSSBS-0828R-CY3
Beschreibung:
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1247R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1247R-A555
Lokale Artikelnummer::
BOSSBS-1247R-A555
Beschreibung:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1247R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1247R-A680
Lokale Artikelnummer::
BOSSBS-1247R-A680
Beschreibung:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8299R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8299R-HRP
Lokale Artikelnummer::
BOSSBS-8299R-HRP
Beschreibung:
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1247R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1247R-FITC
Lokale Artikelnummer::
BOSSBS-1247R-FITC
Beschreibung:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7066R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7066R-FITC
Lokale Artikelnummer::
BOSSBS-7066R-FITC
Beschreibung:
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase /c-Jun N-terminal kinase (SAPK/JNK)
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2420R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2420R-FITC
Lokale Artikelnummer::
BOSSBS-2420R-FITC
Beschreibung:
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2982R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2982R-A647
Lokale Artikelnummer::
BOSSBS-2982R-A647
Beschreibung:
This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 >PACAP-38.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2216R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2216R-FITC
Lokale Artikelnummer::
BOSSBS-2216R-FITC
Beschreibung:
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2420R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2420R-A647
Lokale Artikelnummer::
BOSSBS-2420R-A647
Beschreibung:
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0231R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0231R-A488
Lokale Artikelnummer::
BOSSBS-0231R-A488
Beschreibung:
Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades; the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylates PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and thereby mediates activation of the AKT1 signaling pathway. Mediates activation of HRAS and of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3 and STAT5A and/or STAT5B. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3848R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3848R-A350
Lokale Artikelnummer::
BOSSBS-3848R-A350
Beschreibung:
Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context. Displays barbed-end actin capping activity when associated with ABI1, thereby regulating actin-based motility process: capping activity is auto-inhibited and inhibition is relieved upon ABI1 interaction. Also shows actin bundling activity when associated with BAIAP2, enhancing BAIAP2-dependent membrane extensions and promoting filopodial protrusions. Involved in the regulation of processes such as axonal filopodia growth, stereocilia length, dendritic cell migration and cancer cell migration and invasion. Acts as a regulator of axonal filopodia formation in neurons: in the absence of neurotrophic factors, negatively regulates axonal filopodia formation via actin-capping activity. In contrast, it is phosphorylated in the presence of BDNF leading to inhibition of its actin-capping activity and stimulation of filopodia formation. Component of a complex with DFNB31 and MYO15A that localizes at stereocilia tips and is required for elongation of the stereocilia actin core. Indirectly involved in cell cycle progression; its degradation following ubiquitination being required during G2 phase to promote cell shape changes.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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