Plant+Learning+Activities
Artikel-Nr:
(BOSSBS-7757R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7757R-A555
Lokale Artikelnummer::
BOSSBS-7757R-A555
Beschreibung:
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0163R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0163R-HRP
Lokale Artikelnummer::
BOSSBS-0163R-HRP
Beschreibung:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7757R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7757R-A488
Lokale Artikelnummer::
BOSSBS-7757R-A488
Beschreibung:
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3447R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3447R-A488
Lokale Artikelnummer::
BOSSBS-3447R-A488
Beschreibung:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1778R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1778R-A647
Lokale Artikelnummer::
BOSSBS-1778R-A647
Beschreibung:
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0250R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0250R-CY3
Lokale Artikelnummer::
BOSSBS-0250R-CY3
Beschreibung:
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12431R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12431R-CY7
Lokale Artikelnummer::
BOSSBS-12431R-CY7
Beschreibung:
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1007R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1007R-CY7
Lokale Artikelnummer::
BOSSBS-1007R-CY7
Beschreibung:
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5537R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5537R-CY3
Lokale Artikelnummer::
BOSSBS-5537R-CY3
Beschreibung:
PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10014R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10014R-CY3
Lokale Artikelnummer::
BOSSBS-10014R-CY3
Beschreibung:
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12513R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12513R-A350
Lokale Artikelnummer::
BOSSBS-12513R-A350
Beschreibung:
ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), ARFGAP2 (ADP-ribosylation factor GTPase-activating protein 2) and ARFGAP3 (ADP-ribosylation factor GTPase-activating protein 3) are GTPase-activating proteins (GAP) that are associated with the Golgi apparatus and interact with ADP-ribosylation factor 1 (ARF). These proteins promote hydrolysis of ARF-bound GTP and are required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of ARFGAP1, ARFGAP2 and ARFGAP3 is stimulated by phosphoinosides and inhibited by phosphatidylcholine. The genes encoding ARFGAP1, ARFGAP2 and ARFGAP3 map to human chromosomes 20q13.33, 11p11.2 and 22q13.2, respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12513R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12513R-A555
Lokale Artikelnummer::
BOSSBS-12513R-A555
Beschreibung:
ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), ARFGAP2 (ADP-ribosylation factor GTPase-activating protein 2) and ARFGAP3 (ADP-ribosylation factor GTPase-activating protein 3) are GTPase-activating proteins (GAP) that are associated with the Golgi apparatus and interact with ADP-ribosylation factor 1 (ARF). These proteins promote hydrolysis of ARF-bound GTP and are required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of ARFGAP1, ARFGAP2 and ARFGAP3 is stimulated by phosphoinosides and inhibited by phosphatidylcholine. The genes encoding ARFGAP1, ARFGAP2 and ARFGAP3 map to human chromosomes 20q13.33, 11p11.2 and 22q13.2, respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1178R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1178R-CY5.5
Lokale Artikelnummer::
BOSSBS-1178R-CY5.5
Beschreibung:
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4819R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4819R-A555
Lokale Artikelnummer::
BOSSBS-4819R-A555
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7551R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7551R-A680
Lokale Artikelnummer::
BOSSBS-7551R-A680
Beschreibung:
ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterised human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1074R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1074R-A680
Lokale Artikelnummer::
BOSSBS-1074R-A680
Beschreibung:
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
VE:
1 * 100 µl
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