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Plant+Learning+Activities
Artikel-Nr:
(BOSSBS-9447R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9447R-CY5
Lokale Artikelnummer::
BOSSBS-9447R-CY5
Beschreibung:
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10368R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10368R-CY3
Lokale Artikelnummer::
BOSSBS-10368R-CY3
Beschreibung:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2456R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2456R-A350
Lokale Artikelnummer::
BOSSBS-2456R-A350
Beschreibung:
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9079R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9079R-A647
Lokale Artikelnummer::
BOSSBS-9079R-A647
Beschreibung:
Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1870R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1870R-HRP
Lokale Artikelnummer::
BOSSBS-1870R-HRP
Beschreibung:
Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9079R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9079R-FITC
Lokale Artikelnummer::
BOSSBS-9079R-FITC
Beschreibung:
Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3693R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3693R-CY3
Lokale Artikelnummer::
BOSSBS-3693R-CY3
Beschreibung:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The phosphorylation of the Thr residue by MAP2K7/MKK7 seems to be the prerequisite for JNK activation at least in response to proinflammatory cytokines, while other stimuli activate both MAP2K4/MKK4 and MAP2K7/MKK7 which synergistically phosphorylate JNKs. MAP2K4 is required for maintaining peripheral lymphoid homeostasis. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. Whereas MAP2K7/MKK7 exclusively activates JNKs, MAP2K4/MKK4 additionally activates the p38 MAPKs MAPK11, MAPK12, MAPK13 and MAPK14.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0058R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0058R-A680
Lokale Artikelnummer::
BOSSBS-0058R-A680
Beschreibung:
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5680R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5680R-FITC
Lokale Artikelnummer::
BOSSBS-5680R-FITC
Beschreibung:
Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3362R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3362R-A350
Lokale Artikelnummer::
BOSSBS-3362R-A350
Beschreibung:
Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5680R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5680R-A488
Lokale Artikelnummer::
BOSSBS-5680R-A488
Beschreibung:
Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1812R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1812R-HRP
Lokale Artikelnummer::
BOSSBS-1812R-HRP
Beschreibung:
NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. It affects the implementation of differentiation, proliferation and apoptotic programs. Defects in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (swissprot).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10368R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10368R-CY5
Lokale Artikelnummer::
BOSSBS-10368R-CY5
Beschreibung:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.
VE:
1 * 100 µl
Artikel-Nr:
(USBIP4256-31Y)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P4256-31Y
Lokale Artikelnummer::
USBIP4256-31Y
Beschreibung:
Anti-Plasminogen Activator Inhibitor Type 1, Inhibitory Mouse Monoclonal Antibody [clone: 9L784]
VE:
1 * 1 mg
Artikel-Nr:
(BOSSBS-5756R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5756R
Lokale Artikelnummer::
BOSSBS-5756R
Beschreibung:
Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase promoting factor, or MPF. In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M phase phosphoproteins (MPPs, or MPHOSPHs) permit disassembly of interphase structures and generation of M phase enzymatic activities and structures. VAM1 or MPP6 is thought to be a nucleolus specific exosome co factor, required for its role in the maturation of 5.8S rRNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8680R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8680R-FITC
Lokale Artikelnummer::
BOSSBS-8680R-FITC
Beschreibung:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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