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Artikel-Nr:
(PRSI5467P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5467P
Lokale Artikelnummer::
PRSI5467P
Beschreibung:
SLAIN1 peptide is used for blocking the activity of SLAIN1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-371)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-371
Lokale Artikelnummer::
PRSI91-371
Beschreibung:
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. The protein interacts with MARCH8， human herpesvirus 8 MIR2 protein, adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.It contains 1 Ig-like C2-type(immunoglobulin-like) domainand 1 Ig-like V-type (immunoglobulin-like) domain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-018)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-018
Lokale Artikelnummer::
PRSI91-018
Beschreibung:
At least 23 different variants of IFN- alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN- alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN- alpha subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-292)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-292
Lokale Artikelnummer::
PRSI92-292
Beschreibung:
Glia maturation factor beta (GMFB) contains a ADF-H domain，which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-226)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-226
Lokale Artikelnummer::
PRSI92-226
Beschreibung:
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-922)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-922
Lokale Artikelnummer::
PRSI91-922
Beschreibung:
Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. The gene encoding PIK3IP1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIXW-RP3126)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-RP3126
Lokale Artikelnummer::
PRSIXW-RP3126
Beschreibung:
KHK encodes the gene ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The splice variant presented encodes the highly active form found in liver, renal cortex, and small intestine, while the alternate variant encodes the lower activity form found in most other tissues.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-600)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-600
Lokale Artikelnummer::
PRSI96-600
Beschreibung:
Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.
VE:
1 * 25 µG
Artikel-Nr:
(PRSI5585P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5585P
Lokale Artikelnummer::
PRSI5585P
Beschreibung:
NANOG peptide is used for blocking the activity of NANOG antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-349)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-349
Lokale Artikelnummer::
PRSI92-349
Beschreibung:
Promotilin is a 115 amino acids protein that belongs to the motilin family. It is a secreted protein that plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7193P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7193P
Lokale Artikelnummer::
PRSI7193P
Beschreibung:
19 amino acids near the center of human TPT1.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7201P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7201P
Lokale Artikelnummer::
PRSI7201P
Beschreibung:
17 amino acids near the carboxy terminus of human CCL2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-221)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-221
Lokale Artikelnummer::
PRSI91-221
Beschreibung:
Nucleoside-Diphosphate Kinases (NDKs) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDKs Possesse nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. NDKs involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression and required for neural development including neural patterning and cell fate determination. Prokaryotic NDK forms a functional homotetramer.There are two isoforms of NDK in humans: NDK-A and NDK-B. Both have very similar structure, and can combine in any proportion to form functional NDK hexamers.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6027P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6027P
Lokale Artikelnummer::
PRSI6027P
Beschreibung:
MFSD2B peptide is used for blocking the activity of MFSD2B antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-151)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-151
Lokale Artikelnummer::
PRSI92-151
Beschreibung:
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumour cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signalling specifically induces lytic activity against several tumour cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3647P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3647P
Lokale Artikelnummer::
PRSI3647P
Beschreibung:
TLR5 peptide is used for blocking the activity of TLR5 antibody.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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