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4-(1H-Imidazol-1-yl)benzonitrile


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Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-1910R-A680
Lokale Artikelnummer:: BOSSBS-1910R-A680
Beschreibung:   Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localises transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
VE:  1 * 100 µl
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2960R-HRP
Lokale Artikelnummer:: BOSSBS-2960R-HRP
Beschreibung:   Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2960R-A488
Lokale Artikelnummer:: BOSSBS-2960R-A488
Beschreibung:   Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:  1 * 100 µl
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3034R-HRP
Lokale Artikelnummer:: BOSSBS-3034R-HRP
Beschreibung:   This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
VE:  1 * 100 µl
Lieferant:  Alfa Aesar
Beschreibung:   4-Sulfobenzoesäure Monokaliumsalz 95%
Lieferant:  APOLLO SCIENTIFIC
Beschreibung:   Erbiumtrichlorid, wasserfrei 99,9%

Lieferant:  Merck
Hersteller-Artikelnummer:: 1.16992.0001
Lokale Artikelnummer:: MERC1.16992.0001
Beschreibung:   Streifen für die Verwendung mit RQflex 10, RQflex 10 plus und RQflex® 20.
VE:  1 * 50 Tests
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11661R-FITC
Lokale Artikelnummer:: BOSSBS-11661R-FITC
Beschreibung:   Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008].
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-11661R-CY7)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11661R-CY7
Lokale Artikelnummer:: BOSSBS-11661R-CY7
Beschreibung:   Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008].
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-11661R)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11661R
Lokale Artikelnummer:: BOSSBS-11661R
Beschreibung:   Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008].
VE:  1 * 100 µl
Lieferant:  Alfa Aesar
Beschreibung:   Digadoliniumtrioxid ≥99,99% (REO, Basis der Oxide der Metalle der seltenen Erden), REacton®
Lieferant:  Alfa Aesar
Beschreibung:   These optical crystal windows are ideal for infrared spectroscopy.
Lieferant:  Alfa Aesar
Beschreibung:   Indiumphosphid ≥99,999% (Metall-Basis)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-9930R-A680
Lokale Artikelnummer:: BOSSBS-9930R-A680
Beschreibung:   Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with KCNQ1/KVLTQ1 and elicit a voltage-independent current. May associate with HCN1 and HCN2 and increase potassium current.
VE:  1 * 100 µl
Lieferant:  Alfa Aesar
Beschreibung:   Molybdäntrichlorid ≥99,5% (Metall-Basis)
Lieferant:  VWR Collection
Beschreibung:   Dieses Zwei-in-Eins-Laborwassersystem stellt aus Leitungswasser Reinst- (Typ I) und RO-Wasser (Typ III) her. Die Qualität des Reinstwassers erfüllt oder übertrifft ASTM-, CLSI-, CAP-, und ISO-Typ-I-Wasserstandards.
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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