Potassium+hexacyanocobaltate(III)
Artikel-Nr:
(34266-1L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
34266-1L
Lokale Artikelnummer::
HONC34266-1L
Beschreibung:
Kaliumpermanganat 0.01 M KMnO4 (0.05N) volumetrische Lösung, Fluka™
VE:
1 * 1 L
Lieferant:
Sigma-Aldrich
Beschreibung:
Antimon(III)oxid, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Antimon(III)oxid, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Phosphor(III)bromid, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-10448R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10448R-A750
Lokale Artikelnummer::
BOSSBS-10448R-A750
Beschreibung:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5362R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5362R-A680
Lokale Artikelnummer::
BOSSBS-5362R-A680
Beschreibung:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilises existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10451R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10451R-A750
Lokale Artikelnummer::
BOSSBS-10451R-A750
Beschreibung:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5362R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5362R-A750
Lokale Artikelnummer::
BOSSBS-5362R-A750
Beschreibung:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilises existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3495R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3495R-A647
Lokale Artikelnummer::
BOSSBS-3495R-A647
Beschreibung:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1. Also prevents autophagy through phosphorylation of the autophagy inhibitor DAP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3494R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3494R-A680
Lokale Artikelnummer::
BOSSBS-3494R-A680
Beschreibung:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL203009-50G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
203009-50G
Lokale Artikelnummer::
SIAL203009-50G
Beschreibung:
Cer(III)sulfat Octahydrat, Sigma-Aldrich®
VE:
1 * 50 g
Lieferant:
MP Biomedicals
Beschreibung:
Potassium chloride is a salt commonly used in the preparation of phosphate buffered saline and for the extraction and solubilization of proteins.It is a good potassium source. Also used in the hypotonic KCl-propidium iodide protocol for univariate analysis of metaphase chromosomes; dissociation of eukaryotic ribosomes into subunits by high concentrations of potassium (0.3-1.0 M); preparation of mitochondria, provides an ionic osmotic support for those tissues that assume a gelatinous consistency upon homogenization.
Artikel-Nr:
(BOSSBS-8498R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8498R-A680
Lokale Artikelnummer::
BOSSBS-8498R-A680
Beschreibung:
REG1 beta is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. REG1 beta highly similar to the REG1 alpha protein. The related REG1 alpha protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1 alpha, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8498R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8498R-A647
Lokale Artikelnummer::
BOSSBS-8498R-A647
Beschreibung:
REG1 beta is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. REG1 beta highly similar to the REG1 alpha protein. The related REG1 alpha protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1 alpha, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15514R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15514R-A647
Lokale Artikelnummer::
BOSSBS-15514R-A647
Beschreibung:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9054R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9054R-A680
Lokale Artikelnummer::
BOSSBS-9054R-A680
Beschreibung:
DOM3Z, also known as NG6 or DOM3L, is a 396 amino acid ubiquitously expressed protein belonging to the Dom3Z family. The gene encoding DOM3Z maps to human chromosome 6 in the major histocompatibility complex (MHC) class III region. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome are all associated with genes that map to chromosome 6.
VE:
1 * 100 µl
Preis auf Anfrage
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