2-(Carboxymethyl)-6-fluorobenzoic+acid
Artikel-Nr:
(BOSSBS-12177R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12177R
Lokale Artikelnummer::
BOSSBS-12177R
Beschreibung:
Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12177R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12177R-CY3
Lokale Artikelnummer::
BOSSBS-12177R-CY3
Beschreibung:
Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5875R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5875R-A680
Lokale Artikelnummer::
BOSSBS-5875R-A680
Beschreibung:
Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(84750.600)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC84750.600
Beschreibung:
Linearitätsstandards in dauerhaft versiegelten UV-Küvetten oder in 100-ml-Braunglasflaschen.
VE:
1 * 1 SET
Artikel-Nr:
(BOSSBS-5875R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5875R-A488
Lokale Artikelnummer::
BOSSBS-5875R-A488
Beschreibung:
Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Bortrifluorid-Methanol-Komplex 50% in Methanol, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-5356R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5356R-A647
Lokale Artikelnummer::
BOSSBS-5356R-A647
Beschreibung:
Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12174R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12174R-A647
Lokale Artikelnummer::
BOSSBS-12174R-A647
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12175R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12175R-A647
Lokale Artikelnummer::
BOSSBS-12175R-A647
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12175R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12175R-A350
Lokale Artikelnummer::
BOSSBS-12175R-A350
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6671R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6671R-CY5.5
Lokale Artikelnummer::
BOSSBS-6671R-CY5.5
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6671R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6671R-A488
Lokale Artikelnummer::
BOSSBS-6671R-A488
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
2-Brom-6-nitro-4-(trifluormethyl)anilin
Artikel-Nr:
(BOSSBS-2436R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2436R-CY5.5
Lokale Artikelnummer::
BOSSBS-2436R-CY5.5
Beschreibung:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2436R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2436R-CY7
Lokale Artikelnummer::
BOSSBS-2436R-CY7
Beschreibung:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12171R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12171R-A680
Lokale Artikelnummer::
BOSSBS-12171R-A680
Beschreibung:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.
VE:
1 * 100 µl
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