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1-(2-Hydroxyethyl)imidazole
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1-(2-Hydroxyethyl)imidazole
Artikel-Nr:
(BOSSBS-8546R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8546R-A750
Lokale Artikelnummer::
BOSSBS-8546R-A750
Beschreibung:
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localisation of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilisation. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8546R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8546R-CY5.5
Lokale Artikelnummer::
BOSSBS-8546R-CY5.5
Beschreibung:
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
VE:
1 * 100 µl
Artikel-Nr:
(ACRO408060250)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
408060250
Lokale Artikelnummer::
ACRO408060250
Beschreibung:
Appearance: Clear light yellow Liquid
VE:
1 * 25 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-2-amino-5-methyl-4-phenyl-3-thiophencarboxylat 95%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Ethyl-4-methyl-1H-imidazole-5-carbaldehyde
Artikel-Nr:
(BOSSBS-0185R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0185R-CY3
Lokale Artikelnummer::
BOSSBS-0185R-CY3
Beschreibung:
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3148R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3148R
Lokale Artikelnummer::
BOSSBS-3148R
Beschreibung:
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4110R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4110R-CY5
Lokale Artikelnummer::
BOSSBS-4110R-CY5
Beschreibung:
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8878R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8878R-CY7
Lokale Artikelnummer::
BOSSBS-8878R-CY7
Beschreibung:
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR15442-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR15442-1G
Lokale Artikelnummer::
APOSOR15442-1G
Beschreibung:
Ethyl-2-(5-methoxy-1H-indol-3-yl)-2-oxoacetate
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD29338-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD29338-25G
Lokale Artikelnummer::
BLDPBD29338-25G
Beschreibung:
3-Chloro-pyrazine-2-carboxylic acid ethyl ester 98%
VE:
1 * 25 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl Imidazo[1,2-a]pyridine-5-carboxylate
Artikel-Nr:
(APOSOR17990-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR17990-250MG
Lokale Artikelnummer::
APOSOR17990-250MG
Beschreibung:
tert-Butyl [2-(4-aminophenoxy)ethyl]carbamate
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-2652R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2652R
Lokale Artikelnummer::
BOSSBS-2652R
Beschreibung:
Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
VE:
1 * 100 µl
Artikel-Nr:
(7199-00)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR7199-00
Beschreibung:
J.T.Baker® BAKERBOND®, Ethyl (C₂), BAKERBOND®, 40 µm, 60 Å
VE:
1 * 100 g
Artikel-Nr:
(APOSPC520115-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC520115-1G
Lokale Artikelnummer::
APOSPC520115-1G
Beschreibung:
Ethyl 3-(difluoromEthyl)-1H-indole-2-carboxylate
VE:
1 * 1 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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