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Quecksilber(II)trifluormethansulfonat
Artikel-Nr:
(EHERC12030000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C12030000
Lokale Artikelnummer::
EHERC12030000
Beschreibung:
Mitotan
VE:
1 * 0,1 g
Artikel-Nr:
(BOSSBS-15350R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15350R-A750
Lokale Artikelnummer::
BOSSBS-15350R-A750
Beschreibung:
C9orf96, also known as Protein kinase-like protein SgK071, is a 680 amino acid protein that belongs to the Ser/Thr protein kinase family of the protein kinase superfamily. There are three isoforms of C9orf96 that are produced as a result of alternative splicing events. The gene encoding C9orf96 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE11057305-1G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
11057305-1G
Lokale Artikelnummer::
MOLE11057305-1G
Beschreibung:
(S)-(-)-1,1'-Bi-2-naphthol
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-12330R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12330R-A680
Lokale Artikelnummer::
BOSSBS-12330R-A680
Beschreibung:
The tripartite motif (TRIM) family of proteins are characterised by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å and IFN-, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
VE:
1 * 100 µl
Lieferant:
TUTTNAUER
Beschreibung:
Die Laborautoklaven von Tuttnauer decken ein breites Anwendungsspektrum ab, und sind für viele unterschiedliche Bereiche, wie Forschungsinstitute, Universitäten und die Pharma-, Lebensmittel-, Medizin- und Biotechnologieindustrie geeignet. Die fortschrittliche Labor-Serie ist in einem umfassenden Portfolio hochwertiger, zuverlässiger Tischmodelle (Frontbeladung) und vertikaler Modelle (Beladung von oben) mit Kammervolumen von 23 bis 160 Litern erhältlich, und bietet damit eine Lösung für das gesamte Spektrum der Sterilisationsanforderungen. Die Autoklaven können vollständig konfiguriert werden, von der allgemeinen bis hin zu kundenspezifischen Anwendungen. Die Geräte der Reihen Essential oder Hi End können mit verschiedenen Ausstattungsoptionen individuell an spezifischere oder anspruchsvollere Anwendungen angepasst werden. Der Sterilisationstemperaturbereich reicht von 105 bis 138 °C.
Artikel-Nr:
(BOSSBS-9748R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R-A680
Lokale Artikelnummer::
BOSSBS-9748R-A680
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9748R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R-A750
Lokale Artikelnummer::
BOSSBS-9748R-A750
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8594R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8594R-A350
Lokale Artikelnummer::
BOSSBS-8594R-A350
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(EHERL20000400IO)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
L20000400IO
Lokale Artikelnummer::
EHERL20000400IO
Beschreibung:
Organic Standard, 2,2'-Dichlorbiphenyl (PCB Nr. 4) 10 µg/ml in Isooctan, Packung: Glasflasche
VE:
1 * 10 mL
Artikel-Nr:
(PRSI7593)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7593
Lokale Artikelnummer::
PRSI7593
Beschreibung:
Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation. Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells. IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles.
VE:
1 * 100 µG
Lieferant:
MACHEREY-NAGEL
Beschreibung:
Septen, Silikon virginal/PTFE farblos, Härte: 45° shore A, Stärke: 3,2 mm, Ø: 22 mm
Lieferant:
Sigma-Aldrich
Beschreibung:
Diethylenglycol, Sigma-Aldrich®
Lieferant:
MARIENFELD
Beschreibung:
Hergestellt aus chemisch beständigem Borosilikatglas D 263™ M, hydrolytische Klasse I
Artikel-Nr:
(BOSSBS-12495R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-A350
Lokale Artikelnummer::
BOSSBS-12495R-A350
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-A350
Lokale Artikelnummer::
BOSSBS-13343R-A350
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-CY7
Lokale Artikelnummer::
BOSSBS-13343R-CY7
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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