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Artikel-Nr:
(BOSSBS-2960R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2960R-A750
Lokale Artikelnummer::
BOSSBS-2960R-A750
Beschreibung:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterised by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-[N,N-Bis(trifluoromethanesulphonyl)amino]-5-chloropyridine
Artikel-Nr:
(BOSSBS-12173R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12173R-A647
Lokale Artikelnummer::
BOSSBS-12173R-A647
Beschreibung:
KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12172R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12172R-CY7
Lokale Artikelnummer::
BOSSBS-12172R-CY7
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(CHMPFL13095.POR)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL13095.POR
Lokale Artikelnummer::
CHMPFL13095.POR
Beschreibung:
3-Chlor-2-nitrobenzotrifluorid
VE:
1 * 1 ST
Artikel-Nr:
(SIAL510254-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
510254-5G
Lokale Artikelnummer::
SIAL510254-5G
Beschreibung:
Ethyltrifluorpyruvat, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(REST35616)
Lieferant:
Restek
Hersteller-Artikelnummer::
35616
Lokale Artikelnummer::
REST35616
Beschreibung:
Acylation derivatization reagent.
VE:
1 * 10 ST
Lieferant:
Alfa Aesar
Beschreibung:
Kaliumiodid ≥99,998% (Metall-Basis), Puratronic®
Artikel-Nr:
(BOSSBS-3034R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3034R-A350
Lokale Artikelnummer::
BOSSBS-3034R-A350
Beschreibung:
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL217727-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
217727-25G
Lokale Artikelnummer::
SIAL217727-25G
Beschreibung:
4-Chlor-2-(trifluormethyl)anilin, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-6760R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6760R-CY5.5
Lokale Artikelnummer::
BOSSBS-6760R-CY5.5
Beschreibung:
Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.
VE:
1 * 100 µl
Lieferant:
FLUOROCHEM
Beschreibung:
1,1,1-Trifluoraceton
Lieferant:
Thermo Scientific
Beschreibung:
Kaliumiodid 99.995% (bezogen auf die Metalle der seltenen Erden), reinst
Artikel-Nr:
(BOSSBS-7689R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7689R
Lokale Artikelnummer::
BOSSBS-7689R
Beschreibung:
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
VE:
1 * 100 µl
Artikel-Nr:
(87815.290)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC87815.290
Beschreibung:
Starting materials:
Solution A. Copper sulfate R/ Water R Solution B. anhydrous Sodium carbonate R / Potassium sodium tartrate R/ Sodium hydrogen carbonate R/ anhydrous Sodium sulfate R/ Water R
VE:
1 * 1 L
Lieferant:
Alfa Aesar
Beschreibung:
tri-Kaliumcitrat Monohydrat ≥99%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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