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2-(Ethoxycarbonyl)isonicotinic+acid
Artikel-Nr:
(PRSI28-248)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-248
Lokale Artikelnummer::
PRSI28-248
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member and the KCNA5 gene product assemble into a heteromultimeric A-type channel that inactivates completely and is significantly faster than other A-type Kv channels.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-484)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-484
Lokale Artikelnummer::
PRSI26-484
Beschreibung:
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. KCNK4 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. It homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-6252R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6252R-A647
Lokale Artikelnummer::
BOSSBS-6252R-A647
Beschreibung:
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6252R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6252R-A555
Lokale Artikelnummer::
BOSSBS-6252R-A555
Beschreibung:
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(LOVI517722BT)
Lieferant:
Lovibond Tintometer
Hersteller-Artikelnummer::
517722BT
Lokale Artikelnummer::
LOVI517722BT
Beschreibung:
Test kit, Kaliumiodid / Acidifying GP, Messbereich: 10 - 300 mg/L Cl₂, Für Gerät: MD 600
VE:
1 * 1 KIT
Artikel-Nr:
(LONZBP10-548E)
Lieferant:
LONZA
Hersteller-Artikelnummer::
BP10-548E
Lokale Artikelnummer::
LONZBP10-548E
Beschreibung:
Ammonium-Chloride-Potassium (ACK) Lysing Buffer is used to lyse red blood cells in preparations containing white blood cells.
VE:
1 * 100 mL
Artikel-Nr:
(BSBTPA1047-1)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PA1047-1
Lokale Artikelnummer::
BSBTPA1047-1
Beschreibung:
Rabbit IgG polyclonal antibody for Intermediate conductance calcium-activated potassium channel protein 4(KCNN4) detection. Tested with WB in Human;Mouse;Rat.
VE:
1 * 100 µG
Artikel-Nr:
(BSBTPA2297)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PA2297
Lokale Artikelnummer::
BSBTPA2297
Beschreibung:
Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 4(KCNA4) detection. Tested with WB in Human, Mouse, Rat.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-296)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-296
Lokale Artikelnummer::
PRSI28-296
Beschreibung:
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product.
VE:
1 * 100 µG
Artikel-Nr:
(720-0359)
Lieferant:
RAL
Hersteller-Artikelnummer::
361850-0000
Lokale Artikelnummer::
RALA361850-0000
Beschreibung:
In an acid environment, ferric ions react with Potassium Ferrocyanide to form a precipitate: Ferric Ferrocyanide (or Prussian Blue), that shows the presence of the pathological pigment, Haemosiderin.This pigment is found in the liver and in bone marrow in diseases such as Haemochromatosis, Cirrhosis and some anemia.
VE:
1 * 1 KIT
Artikel-Nr:
(PRSI25-884)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-884
Lokale Artikelnummer::
PRSI25-884
Beschreibung:
ABCC9 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.
VE:
1 * 50 µG
Lieferant:
Alfa Aesar
Beschreibung:
Contains: 120 mM sodium chloride, 5 mM potassium chloride, 2 mM calcium chloride, 1 mM magnesium chloride, 25 mM sodium bicarbonate, and 5,5 mM D-glucose.
Artikel-Nr:
(APOSPC105414-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC105414-25G
Lokale Artikelnummer::
APOSPC105414-25G
Beschreibung:
Potassium Trifluoro(5-Formylfuran-2-Yl)Borate 25g pack 1 * 25 g
VE:
1 * 25 g
New Product
Artikel-Nr:
(PRSI28-240)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-240
Lokale Artikelnummer::
PRSI28-240
Beschreibung:
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.
VE:
1 * 100 µG
Artikel-Nr:
(SIAL25510-500G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
25510-500G
Lokale Artikelnummer::
SIAL25510-500G
Beschreibung:
di-Kalium-L(+)-tartrat Hemihydrat, Sigma-Aldrich®
VE:
1 * 500 g
Artikel-Nr:
(APOSPC105414-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC105414-5G
Lokale Artikelnummer::
APOSPC105414-5G
Beschreibung:
Potassium Trifluoro(5-Formylfuran-2-Yl)Borate 5g pack 1 * 5 g
VE:
1 * 5 g
New Product
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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