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Proteine+und+Peptide
Artikel-Nr:
(BOSSBS-11178R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11178R-A555
Lokale Artikelnummer::
BOSSBS-11178R-A555
Beschreibung:
The endoplasmic reticulum exerts a quality control over newly synthesized proteins and a variety of components have been implicated in the specific recognition of aberrant or misfolded polypeptides. Signal peptide peptidase (SPP) catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. SPP is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides, and may play a role in graft rejection. It also may be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11178R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11178R-A488
Lokale Artikelnummer::
BOSSBS-11178R-A488
Beschreibung:
The endoplasmic reticulum exerts a quality control over newly synthesized proteins and a variety of components have been implicated in the specific recognition of aberrant or misfolded polypeptides. Signal peptide peptidase (SPP) catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. SPP is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides, and may play a role in graft rejection. It also may be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11178R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11178R-HRP
Lokale Artikelnummer::
BOSSBS-11178R-HRP
Beschreibung:
The endoplasmic reticulum exerts a quality control over newly synthesized proteins and a variety of components have been implicated in the specific recognition of aberrant or misfolded polypeptides. Signal peptide peptidase (SPP) catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. SPP is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides, and may play a role in graft rejection. It also may be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11178R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11178R-FITC
Lokale Artikelnummer::
BOSSBS-11178R-FITC
Beschreibung:
The endoplasmic reticulum exerts a quality control over newly synthesized proteins and a variety of components have been implicated in the specific recognition of aberrant or misfolded polypeptides. Signal peptide peptidase (SPP) catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. SPP is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides, and may play a role in graft rejection. It also may be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Biotium bietet eine Auswahl an Formaten mit Reaktivfarbstoffen zum Markieren von Proteinen, Nukleinsäuren und anderen Biomolekülen mit Fluoreszenzfarbstoffen an. CF®-Farbstoffe haben Vorteile in Bezug auf Helligkeit und Photostabilität im Vergleich zu anderen ähnlichen kommerziellen Farbstoffen. CF®-Farbstoffe sind in einer Reihe von Formaten für CF®-Farbstofffarben erhältlich, die das sichtbare und nahe Infrarotspektrum abdecken.
Artikel-Nr:
(BOSSBS-0539R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0539R-A647
Lokale Artikelnummer::
BOSSBS-0539R-A647
Beschreibung:
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0539R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0539R-FITC
Lokale Artikelnummer::
BOSSBS-0539R-FITC
Beschreibung:
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2199R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2199R
Lokale Artikelnummer::
BOSSBS-2199R
Beschreibung:
The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4908R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4908R-CY3
Lokale Artikelnummer::
BOSSBS-4908R-CY3
Beschreibung:
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4908R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4908R-CY5
Lokale Artikelnummer::
BOSSBS-4908R-CY5
Beschreibung:
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1296R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1296R-A750
Lokale Artikelnummer::
BOSSBS-1296R-A750
Beschreibung:
Beta-defensin 2 (BD-2) also known as skin-antimicrobial peptide 1 (SAP1) is a peptide that is encoded by the DEFB4 (defensin, beta 4) gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta-defensin 2 is an antibiotic peptide which is locally regulated by inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1296R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1296R-FITC
Lokale Artikelnummer::
BOSSBS-1296R-FITC
Beschreibung:
Beta-defensin 2 (BD-2) also known as skin-antimicrobial peptide 1 (SAP1) is a peptide that is encoded by the DEFB4 (defensin, beta 4) gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta-defensin 2 is an antibiotic peptide which is locally regulated by inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1296R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1296R-A555
Lokale Artikelnummer::
BOSSBS-1296R-A555
Beschreibung:
Beta-defensin 2 (BD-2) also known as skin-antimicrobial peptide 1 (SAP1) is a peptide that is encoded by the DEFB4 (defensin, beta 4) gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta-defensin 2 is an antibiotic peptide which is locally regulated by inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1296R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1296R-A680
Lokale Artikelnummer::
BOSSBS-1296R-A680
Beschreibung:
Beta-defensin 2 (BD-2) also known as skin-antimicrobial peptide 1 (SAP1) is a peptide that is encoded by the DEFB4 (defensin, beta 4) gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta-defensin 2 is an antibiotic peptide which is locally regulated by inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2374R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2374R-CY3
Lokale Artikelnummer::
BOSSBS-2374R-CY3
Beschreibung:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2374R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2374R-CY7
Lokale Artikelnummer::
BOSSBS-2374R-CY7
Beschreibung:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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