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Proteine+und+Peptide
Artikel-Nr:
(BOSSBS-5897R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5897R-HRP
Lokale Artikelnummer::
BOSSBS-5897R-HRP
Beschreibung:
Endothelins are vasoactive proteins derived form the endothelium The active form of this protein is a 21aa peptide processed from the precursor. The active peptide binds endothelin receptor type B (EDNRB). This interaction EDNRB regulates the development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in Endothelin 3 and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0112M-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0112M-A750
Lokale Artikelnummer::
BOSSBS-0112M-A750
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1559R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1559R-HRP
Lokale Artikelnummer::
BOSSBS-1559R-HRP
Beschreibung:
This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1559R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1559R-A750
Lokale Artikelnummer::
BOSSBS-1559R-A750
Beschreibung:
This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5983R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5983R-A488
Lokale Artikelnummer::
BOSSBS-5983R-A488
Beschreibung:
AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0018R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0018R-CY5.5
Lokale Artikelnummer::
BOSSBS-0018R-CY5.5
Beschreibung:
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0018R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0018R
Lokale Artikelnummer::
BOSSBS-0018R
Beschreibung:
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5912R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5912R-A750
Lokale Artikelnummer::
BOSSBS-5912R-A750
Beschreibung:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerisation of proline imidic peptide bonds in oligopeptides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0347R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0347R-A350
Lokale Artikelnummer::
BOSSBS-0347R-A350
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5168R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5168R-FITC
Lokale Artikelnummer::
BOSSBS-5168R-FITC
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3028R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3028R-FITC
Lokale Artikelnummer::
BOSSBS-3028R-FITC
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2374R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2374R-A680
Lokale Artikelnummer::
BOSSBS-2374R-A680
Beschreibung:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2374R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2374R-CY5
Lokale Artikelnummer::
BOSSBS-2374R-CY5
Beschreibung:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5168R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5168R-CY3
Lokale Artikelnummer::
BOSSBS-5168R-CY3
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0112M-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0112M-CY5.5
Lokale Artikelnummer::
BOSSBS-0112M-CY5.5
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5168R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5168R
Lokale Artikelnummer::
BOSSBS-5168R
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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