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Pyrazolo[1,5-a]pyrimidin-7(4H)-one
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Pyrazolo[1,5-a]pyrimidin-7(4H)-one
Artikel-Nr:
(BOSSBS-8641R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8641R-CY7
Lokale Artikelnummer::
BOSSBS-8641R-CY7
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.
VE:
1 * 100 µl
Lieferant:
ENTEGRIS
Beschreibung:
Konische Tasche fasst einen Wafer mit aktiver Seite nach unten, wobei nur die Kanten des Wafers berührt werden.
Artikel-Nr:
(172-0063)
Lieferant:
Merck
Hersteller-Artikelnummer::
ZIQELEMT0
Lokale Artikelnummer::
MILLZIQELEMT0
Beschreibung:
Milli-Q® IQ Element water purification and dispensing unit is designed to fit into your trace analysis workflow. The Milli-Q® IQ Element unit, combined with a Milli-Q® IQ 7 series water purification system, delivers analytical grade ultrapure water that is suitable for trace and ultra-trace elemental analyses, including ICP-MS, GF-AAS and trace IC.
VE:
1 * 1 ST
Lieferant:
Alfa Aesar
Beschreibung:
2,7-Dinitro-9-fluorenon ≥97%
Artikel-Nr:
(MLDVGENEPIX4100A-U)
Lieferant:
Molecular Devices
Hersteller-Artikelnummer::
GENEPIX4100A-U
Lokale Artikelnummer::
MLDVGENEPIX4100A-U
Beschreibung:
GenePix® 4100A Microarray Scanner offers its simplicity, reliability and flexibility in microarray-based research, be it in genomics, proteomics, or novel applications. It has all the quality, sensitivity, reliability and ease-of use of more expensive scanners, but in a price range and bench top footprint that makes it ideal for individual lab use.
VE:
1 * 1 ST
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Perfluoro(2-methyl-3-pentanone)
Lieferant:
Alfa Aesar
Beschreibung:
1-Phenyl-1-decanon ≥98%
Artikel-Nr:
(BOSSBS-5951R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5951R-HRP
Lokale Artikelnummer::
BOSSBS-5951R-HRP
Beschreibung:
Effector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.
VE:
1 * 100 µl
Lieferant:
BLD PHARMATECH GMBH
Beschreibung:
[5,10,15,20-Tetrakis(4-methoxyphenyl)porphyrinato]cobalt(II) 95%
Artikel-Nr:
(BOSSBS-11753R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11753R-A350
Lokale Artikelnummer::
BOSSBS-11753R-A350
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9144R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9144R-A680
Lokale Artikelnummer::
BOSSBS-9144R-A680
Beschreibung:
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognises and binds proteins that contain destabilising N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9107R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9107R-HRP
Lokale Artikelnummer::
BOSSBS-9107R-HRP
Beschreibung:
The death domain (DD) superfamily of proteins share one or more of the following domains: the DD, DED (death-effector domain), CARD (caspase-recruitment domain) and PYD (Pyrin domain). Each of these domains is characterized by a canonical death domain fold, which consists of a bundle of five or six antiparallel α-helices. As their names suggest, these domains play prominent roles in programmed cell death. ASC2 (apoptosis-associated speck-like protein containing a CARD 2), also known as Pyrin-only protein 1 or PADD-only protein 1, is an 89 amino acid member of the DD superfamily that contains one Pyrin domain. Localized to the cytoplasm, ASC2 interacts with ASC to modulate NF-κB and pro-caspase-1 regulation. ASC2 is predominantly expressed in monocytes, macrophages and granulocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0355-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0355-50
Lokale Artikelnummer::
BTIUBNUM0355-50
Beschreibung:
Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-11823R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11823R-A647
Lokale Artikelnummer::
BOSSBS-11823R-A647
Beschreibung:
PIPPIN is a Y-box protein (also called cold-shock (CSD) domain-containing protein) and belongs to a family of highly conserved RNA-binding transcriptional regulators. Predominantly expressed in brain cells and localizing to the nucleus and the cytoplasm, PIPPIN contains two RNA-binding motifs, namely PIP1 and PIP2, and one CSD domain. PIPPIN functions as a nucleic acid binding regulatory factor and is believed to participate in brain maturation. More specifically, PIPPIN binds to the 3’-UTR ends of the mRNAs encoding Histone H1 and Histone H3.3. This interaction requires all of the PIPPIN domains to work in concert as one functional protein. In addition, PIPPIN can be sumoylated in a thyroid hormone (T3)-dependent manner. This suggests that PIPPIN modification in response to extracellular stimuli may modulate the regulation of protein synthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11753R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11753R-A647
Lokale Artikelnummer::
BOSSBS-11753R-A647
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9144R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9144R-A750
Lokale Artikelnummer::
BOSSBS-9144R-A750
Beschreibung:
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognises and binds proteins that contain destabilising N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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