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Pyridin-N-oxid
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Pyridin-N-oxid
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Bromo-5-(trifluoromethyl)pyridin-2-ol
Artikel-Nr:
(APOSOR2143-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR2143-250MG
Lokale Artikelnummer::
APOSOR2143-250MG
Beschreibung:
3-Aminothieno[2,3-c]pyridine
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-10521R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10521R-CY3
Lokale Artikelnummer::
BOSSBS-10521R-CY3
Beschreibung:
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(Pyridin-2-ylmethyl)(pyridin-3-ylmethyl)amine
Artikel-Nr:
(BOSSBS-11277R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11277R-A647
Lokale Artikelnummer::
BOSSBS-11277R-A647
Beschreibung:
DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11277R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11277R-FITC
Lokale Artikelnummer::
BOSSBS-11277R-FITC
Beschreibung:
DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13544R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13544R-A647
Lokale Artikelnummer::
BOSSBS-13544R-A647
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1446R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1446R-CY7
Lokale Artikelnummer::
BOSSBS-1446R-CY7
Beschreibung:
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilisation of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Thieno[2,3-c]pyridine
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Fluor-5-(trifluormethyl)pyridin 97%
Artikel-Nr:
(BOSSBS-3410R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3410R-CY3
Lokale Artikelnummer::
BOSSBS-3410R-CY3
Beschreibung:
Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Chloro-3-(difluoromethoxy)pyridine
Artikel-Nr:
(APOSPC408811-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC408811-1G
Lokale Artikelnummer::
APOSPC408811-1G
Beschreibung:
2-Chloro-3-(pentafluoroethyl)pyridine
VE:
1 * 1 g
Artikel-Nr:
(APOSPC408809-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC408809-1G
Lokale Artikelnummer::
APOSPC408809-1G
Beschreibung:
2-Chloro-4-(pentafluoroethyl)pyridine
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Bromo-2-(1-pyrrolidinyl)pyridine
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-(Trifluoromethyl)pyridine-3-carboxamideoxime
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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