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7-(Trifluoromethyl)benzothiophene-2-carbonitrile
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7-(Trifluoromethyl)benzothiophene-2-carbonitrile
Lieferant:
Biotium
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Artikel-Nr:
(BOSSBS-0268R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0268R-HRP
Lokale Artikelnummer::
BOSSBS-0268R-HRP
Beschreibung:
Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins. Neurobeachin, is also a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site for the type II regulatory subunit of protein kinase A. Neurobeachin is peripherally associated with pleomorphic tubulovesicular endomembranes near the trans sides of Golgi stacks and throughout the cell body and cell processes. It is also found in a subpopulation of synapses, where it is concentrated at the postsynaptic plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(APOSIN1204-50G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
IN1204-50G
Lokale Artikelnummer::
APOSIN1204-50G
Beschreibung:
Bariumnitrat 99,9%
VE:
1 * 50 g
Artikel-Nr:
(BOSSBS-5968R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5968R-A750
Lokale Artikelnummer::
BOSSBS-5968R-A750
Beschreibung:
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5968R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5968R-A488
Lokale Artikelnummer::
BOSSBS-5968R-A488
Beschreibung:
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11702R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11702R
Lokale Artikelnummer::
BOSSBS-11702R
Beschreibung:
The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R
Lokale Artikelnummer::
BOSSBS-12919R
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11702R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11702R-CY7
Lokale Artikelnummer::
BOSSBS-11702R-CY7
Beschreibung:
The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Artikel-Nr:
(BOSSBS-8241R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8241R-A555
Lokale Artikelnummer::
BOSSBS-8241R-A555
Beschreibung:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2924R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2924R-CY3
Lokale Artikelnummer::
BOSSBS-2924R-CY3
Beschreibung:
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2924R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2924R-CY5
Lokale Artikelnummer::
BOSSBS-2924R-CY5
Beschreibung:
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2924R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2924R-A350
Lokale Artikelnummer::
BOSSBS-2924R-A350
Beschreibung:
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11702R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11702R-A647
Lokale Artikelnummer::
BOSSBS-11702R-A647
Beschreibung:
The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-A488
Lokale Artikelnummer::
BOSSBS-12919R-A488
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-HRP
Lokale Artikelnummer::
BOSSBS-12919R-HRP
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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