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5-Isochinolinborons\u00E4ure+Hydrochlorid
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5-Isochinolinborons\u00E4ure+Hydrochlorid
Artikel-Nr:
(555-9065)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
26RD142F
Lokale Artikelnummer::
HYPE26RD142F
Beschreibung:
These low bleed columns are specifically designed for the analysis of pesticides and it is mainly useful for applications requiring a higher temperature.
VE:
1 * 1 ST
Artikel-Nr:
(SIAL449679-10G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
449679-10G
Lokale Artikelnummer::
SIAL449679-10G
Beschreibung:
Bariumisopropoxid, Sigma-Aldrich®
VE:
1 * 10 g
Artikel-Nr:
(REST31012)
Lieferant:
Restek
Hersteller-Artikelnummer::
31012
Lokale Artikelnummer::
REST31012
Beschreibung:
sv calibration mix #6 contains aldrin, α-bhc, β-bhc, δ-bhc, γ-bhc (lindane), 4,4'-DDD, 4,4'-DDE, 4,4'-DDT, dieldrin, endosulphan I, endosulphan II, endosulphan sulphate, endrin, endrin aldehyde, endrin ketone, heptachlor, heptachlor epoxide (isomer B), methoxychlor.
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-2649R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2649R-A750
Lokale Artikelnummer::
BOSSBS-2649R-A750
Beschreibung:
Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex. LCK then phosphorylates tyrosines residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the cytoplasmic tails of the TCR-gamma chains and CD3 subunits, initiating the TCR/CD3 signaling pathway. Once stimulated, the TCR recruits the tyrosine kinase ZAP7, that becomes phosphorylated and activated by LCK. Following this, a large number of signaling molecules are recruited, ultimately leading to lymphokine production. LCK also contributes to signaling by other receptor molecules. Associates directly with the cytoplasmic tail of CD2, which leads to hyperphosphorylation and activation of LCK. Also plays a role in the IL2 receptor-linked signaling pathway that controls the T-cell proliferative response. Binding of IL2 to its receptor results in increased activity of LCK. Is expressed at all stages of thymocyte development and is required for the regulation of maturation events that are governed by both pre-TCR and mature alpha beta TCR. Phosphorylates other substrates including RUNX3, PTK2B/PYK2, the microtubule-associated protein MAPT, RHOH or TYROBP.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI48-130)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-130
Lokale Artikelnummer::
PRSI48-130
Beschreibung:
CCXCR1 is a Chemokine Receptor expressed in lymphotactin-responsive leukocyte cells. The viral macrophage inflammatory protein-II, vMIP-II (but not vMIP-I), has been found to be an antagonist of lymphotactin activity at CCXCR1. The CCXCR1 gene is located near the genes for C-C chemokine receptor 9 and SIV/HIV receptor Bonzo on chromosome 3. CCXCR1 is associated with inflammatory and immunological responses by regulating the trafficking of T and B lymphocytes and neutrophils. The up-regulation of CCXCR1 in peripheral T cells is correlated with the inflammatory process observed in Crohns disease.
VE:
1 * 50 µG
Artikel-Nr:
(BSBTPA1788)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PA1788
Lokale Artikelnummer::
BSBTPA1788
Beschreibung:
Rabbit IgG polyclonal antibody for HLA class II histocompatibility antigen, DM beta chain (HLA-DMB) detection. Tested with WB, IHC-P in Human.
VE:
1 * 0,1 mg
Artikel-Nr:
(1.00663.9020)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.00663.9020
Lokale Artikelnummer::
MERP1.00663.9020
Beschreibung:
Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
Corresponds to Ph Eur, BP, JP, NF, FCC
VE:
1 * 20 kg
Lieferant:
Biotium
Beschreibung:
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 55 kDa (CK7); 52 kDa (CK8); 56.5 kDa (CK10); 53 kDa (CK13); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 46 kDa (CK17); 45 kDa (CK18) and 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.
Artikel-Nr:
(BOSSBS-1687R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1687R-A680
Lokale Artikelnummer::
BOSSBS-1687R-A680
Beschreibung:
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterised by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localisation, and cellular function. Phosphorylates TPM1, enhancing stress fibre formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. Phosphorylates PRKD1 and regulates JNK signaling by binding and activating PRKD1 under oxidative stress. Phosphorylates BECN1, reducing its interaction with BCL2 and BCL2L1 and promoting the induction of autophagy. Phosphorylates TSC2, disrupting the TSC1-TSC2 complex and stimulating mTORC1 activity in a growth factor-dependent pathway. Phosphorylates RPS6, MYL9 and DAPK3. Acts as a signaling amplifier of NMDA receptors at extrasynaptic sites for mediating brain damage in stroke. Cerebral ischemia recruits DAPK1 into the NMDA receptor complex and it phosphorylates GRINB at Ser-133 inducing injurious Ca(2+) influx through NMDA receptor channels, resulting in an irreversible neuronal death. Required together with DAPK3 for phosphorylation of RPL13A upon interferon-gamma activation which is causing RPL13A involvement in transcript-selective translation inhibition. Isoform 2 cannot induce apoptosis but can induce membrane blebbing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1687R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1687R-FITC
Lokale Artikelnummer::
BOSSBS-1687R-FITC
Beschreibung:
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. Phosphorylates PRKD1 and regulates JNK signaling by binding and activating PRKD1 under oxidative stress. Phosphorylates BECN1, reducing its interaction with BCL2 and BCL2L1 and promoting the induction of autophagy. Phosphorylates TSC2, disrupting the TSC1-TSC2 complex and stimulating mTORC1 activity in a growth factor-dependent pathway. Phosphorylates RPS6, MYL9 and DAPK3. Acts as a signaling amplifier of NMDA receptors at extrasynaptic sites for mediating brain damage in stroke. Cerebral ischemia recruits DAPK1 into the NMDA receptor complex and it phosphorylates GRINB at Ser-133 inducing injurious Ca(2+) influx through NMDA receptor channels, resulting in an irreversible neuronal death. Required together with DAPK3 for phosphorylation of RPL13A upon interferon-gamma activation which is causing RPL13A involvement in transcript-selective translation inhibition. Isoform 2 cannot induce apoptosis but can induce membrane blebbing.
VE:
1 * 100 µl
Artikel-Nr:
(BSBTA00398)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
A00398
Lokale Artikelnummer::
BSBTA00398
Beschreibung:
Rabbit IgG polyclonal antibody for Keratin, type II cytoskeletal 5(KRT5) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-095)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-095
Lokale Artikelnummer::
PRSI25-095
Beschreibung:
TCERG1 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. TCERG1 interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
VE:
1 * 50 µG
Lieferant:
DELTA PLUS
Beschreibung:
Diese Overalls bestehen zu 85% aus Polyester und zu 15% aus Baumwolle und verfügen über ein Nylonfutter sowie eine Thinsulate™ Polsterung. Ideal für extrem kalte Umgebungen.
Lieferant:
MP Biomedicals
Beschreibung:
Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of <i>Micromonospora purpurea</i> or <i>M. echinospora</i>. It inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms.
Artikel-Nr:
(PRSI27-270)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-270
Lokale Artikelnummer::
PRSI27-270
Beschreibung:
SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-220)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-220
Lokale Artikelnummer::
PRSI30-220
Beschreibung:
ST3GAL3 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. ST3GAL3 is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29.The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Multiple transcript variants encoding several different isoforms have been found for this gene.
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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