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SKI-II
Lieferant:
Cayman Chemical
Beschreibung:
Sphingosine kinase isoforms, SPHK 1 and SPHK 2, catalyse the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 (SPHK I<sub>2</sub>) is a potent, selective inhibitor of SPHK 1 with anti-proliferative activity.
Artikel-Nr:
(PRSI27-539)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-539
Lokale Artikelnummer::
PRSI27-539
Beschreibung:
SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly (A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1684R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-A750
Lokale Artikelnummer::
BOSSBS-1684R-A750
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1684R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-A680
Lokale Artikelnummer::
BOSSBS-1684R-A680
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1684R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-CY5
Lokale Artikelnummer::
BOSSBS-1684R-CY5
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1684R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-HRP
Lokale Artikelnummer::
BOSSBS-1684R-HRP
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(USBIS1013-89Z3)
Lieferant:
US Biological
Hersteller-Artikelnummer::
S1013-89Z3
Lokale Artikelnummer::
USBIS1013-89Z3
Beschreibung:
Anti-SKI Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBIS1013-89V)
Lieferant:
US Biological
Hersteller-Artikelnummer::
S1013-89V
Lokale Artikelnummer::
USBIS1013-89V
Beschreibung:
Anti-SKI Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1684R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-CY3
Lokale Artikelnummer::
BOSSBS-1684R-CY3
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1684R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-A350
Lokale Artikelnummer::
BOSSBS-1684R-A350
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(USBIS1013-89W)
Lieferant:
US Biological
Hersteller-Artikelnummer::
S1013-89W
Lokale Artikelnummer::
USBIS1013-89W
Beschreibung:
Anti-Ski-like Protein Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(ABCAAB115553-50)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB115553-50
Lokale Artikelnummer::
ABCAAB115553-50
Beschreibung:
Anti-SKI Rabbit Polyclonal Antibody
VE:
1 * 50 µG
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-1684R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-A488
Lokale Artikelnummer::
BOSSBS-1684R-A488
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1684R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-CY5.5
Lokale Artikelnummer::
BOSSBS-1684R-CY5.5
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(USBI145990)
Lieferant:
US Biological
Hersteller-Artikelnummer::
145990
Lokale Artikelnummer::
USBI145990
Beschreibung:
Anti-SKI Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-1684R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-A647
Lokale Artikelnummer::
BOSSBS-1684R-A647
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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