(2R)-1-(tert-Butoxycarbonyl)piperazine-2-carboxylic+acid
Artikel-Nr:
(BOSSBS-8998R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8998R-A555
Lokale Artikelnummer::
BOSSBS-8998R-A555
Beschreibung:
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12497R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12497R-CY5
Lokale Artikelnummer::
BOSSBS-12497R-CY5
Beschreibung:
Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins (2). The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages (3,4). The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (5–7). The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8). The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10).
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
(1-Ethoxycarbonylcyclopropyl)triphenylphosphoniumtetrafluoroborat ≥98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Kalium(2,4-bis(trifluormethyl)phenyl)trifluoroborat
Artikel-Nr:
(4483-25)
Lieferant:
MACRON AVANTOR BRAND
Lokale Artikelnummer::
MACR4483-25
Beschreibung:
Especially intended for use as an HPLC and TLC solvent.
VE:
1 * 2,5 L
Artikel-Nr:
(SIAL01302-1L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
01302-1L
Lokale Artikelnummer::
SIAL01302-1L
Beschreibung:
Hexafluorokieselsäure 34% in wässriger Lösung, Sigma-Aldrich®
VE:
1 * 1 L
Artikel-Nr:
(80011-2)
Lieferant:
Biotium
Hersteller-Artikelnummer::
80011-2
Lokale Artikelnummer::
BTIU80011-2
Beschreibung:
Calcein AM is a widely used green fluorescent cell marker. Calcein AM is membrane-permeant and thus can be introduced into cells via incubation.
VE:
1 * 1 mL
Lieferant:
EHRENSTORFER
Beschreibung:
Organic Standard, 1,1,2-Trichlorethan, Packung: Glasflasche
Artikel-Nr:
(BOSSBS-3666R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3666R-A647
Lokale Artikelnummer::
BOSSBS-3666R-A647
Beschreibung:
Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100% in various studies; as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30% of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3666R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3666R-FITC
Lokale Artikelnummer::
BOSSBS-3666R-FITC
Beschreibung:
Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100% in various studies; as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30% of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13126R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13126R-A350
Lokale Artikelnummer::
BOSSBS-13126R-A350
Beschreibung:
A gene of chromosome 6q23 encodes the 640 amino acid protein, EYA4 (eyes absent) (1). EYA is one of four members of the eyes absent family (1). A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family (1). EYA4 is expressed in the craniofacial mesenchyme, the dermamyotome, and the limb (1). The conserved region in other EYA proteins interacts with SIX, DACH, and G-proteins, which regulate transcription in early embryonic development (1,2,3,4). SIX translocates EYA1-3 to the nucleus, and G-proteins can stop this interaction (3,4). Premature stop codon mutations in EYA4 cause postlingual, progressive autosomal dominant hearing loss in humans (2). This shows that EYA4 is also vital to the mature organ of Corti (2). EYA4 may cause oculo-dento-digital syndrome, based on its expression pattern and map postion (1).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI4779P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4779P
Lokale Artikelnummer::
PRSI4779P
Beschreibung:
IL-34 peptide is used for blocking the activity of IL-34 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-9737R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9737R-A555
Lokale Artikelnummer::
BOSSBS-9737R-A555
Beschreibung:
The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. EDRF1 (erythroid differentiation-related factor 1), also known as C10orf137 (chromosome 10 open reading frame 137), is a 1,238 amino acid protein containing two TPR repeats. Localizing to nucleus, EDRF1 is involved in transcriptional activation of globin genes by regulating DNA-binding activity of GATA-1 transcription factor. EDRF1 may also play an important role in organ development and histological differentiation. EDRF1 exists as four alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 10q26.13.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12497R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12497R-FITC
Lokale Artikelnummer::
BOSSBS-12497R-FITC
Beschreibung:
Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins (2). The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages (3,4). The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (5–7). The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8). The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8998R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8998R-A488
Lokale Artikelnummer::
BOSSBS-8998R-A488
Beschreibung:
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8998R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8998R-A750
Lokale Artikelnummer::
BOSSBS-8998R-A750
Beschreibung:
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
VE:
1 * 100 µl
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