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spezialf
Korrigiert: "spezialf"
Lieferant:
ANSELL HEALTH CARE
Beschreibung:
Diese beidseitig tragbaren, leichten und dehnbaren Isolierhandschuhe sind aus speziellen Thermolite® Hohlkernfasern gestrickt, welche eine besonders effiziente Wärmeisolationsbarriere zwischen Haut und Umgebung bilden.
Artikel-Nr:
(BOSSBS-1911R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1911R-A350
Lokale Artikelnummer::
BOSSBS-1911R-A350
Beschreibung:
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5636R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5636R-A647
Lokale Artikelnummer::
BOSSBS-5636R-A647
Beschreibung:
Synaptotagmins (Syts) are a large gene family of synaptic vesicle integral membrane proteins. Syt functions as regulators of both exocytosis /endocytosis and is involved in neurotransmitter secretion from small secretory vesicles. 13 isoforms of Syt have been identified(SytI-XIII). SynaptotagminVI is localized to the endoplasmic reticulum and/or Golgi like perinuclear compartment. It may be important for trafficking and calcium signaling as it is specially expressed in nonneuronal tissues. Also SytVI is present in the acrosomal region of mammalian spermatozoa. The cytosolic domain of SytVI can abrogate exocytosis by competing with the endogenous protein for essential interactions with the fusion machinery involved in a acrosomal exocytosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5636R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5636R-A680
Lokale Artikelnummer::
BOSSBS-5636R-A680
Beschreibung:
Synaptotagmins (Syts) are a large gene family of synaptic vesicle integral membrane proteins. Syt functions as regulators of both exocytosis /endocytosis and is involved in neurotransmitter secretion from small secretory vesicles. 13 isoforms of Syt have been identified(SytI-XIII). SynaptotagminVI is localised to the endoplasmic reticulum and/or Golgi like perinuclear compartment. It may be important for trafficking and calcium signaling as it is specially expressed in nonneuronal tissues. Also SytVI is present in the acrosomal region of mammalian spermatozoa. The cytosolic domain of SytVI can abrogate exocytosis by competing with the endogenous protein for essential interactions with the fusion machinery involved in a acrosomal exocytosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1911R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1911R-A555
Lokale Artikelnummer::
BOSSBS-1911R-A555
Beschreibung:
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11186R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11186R
Lokale Artikelnummer::
BOSSBS-11186R
Beschreibung:
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.
VE:
1 * 100 µl
Lieferant:
ANSELL HEALTH CARE
Beschreibung:
Dieser velourisierte Schutzhandschuh mit spezieller Nitrilkautschuk-Beschichtung bietet mit seiner rauen Oberfläche einen sicheren Griff.
Artikel-Nr:
(BOSSBS-11918R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11918R-A350
Lokale Artikelnummer::
BOSSBS-11918R-A350
Beschreibung:
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11918R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11918R-A488
Lokale Artikelnummer::
BOSSBS-11918R-A488
Beschreibung:
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11918R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11918R-A555
Lokale Artikelnummer::
BOSSBS-11918R-A555
Beschreibung:
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11067R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11067R-HRP
Lokale Artikelnummer::
BOSSBS-11067R-HRP
Beschreibung:
Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
VE:
1 * 100 µl
Lieferant:
VWR Chemicals
Beschreibung:
Gefrierspray für die Verwendung vor dem Schneideprozess mit Gefriermikrotom
Artikel-Nr:
(111-0186)
Lieferant:
Nitritex
Hersteller-Artikelnummer::
BCGS1
Lokale Artikelnummer::
NITRBCGS1
Beschreibung:
Diese Brille besteht aus leichtem PVC und bietet einen ausgezeichneten Tragekomfort. Das speziell entwickelte indirekte Belüftungssystem ermöglicht eine gute Belüftung bei gleichzeitiger Verringerung der Partikelfreisetzung.
VE:
1 * 60 ST
Artikel-Nr:
(BOSSBS-5474R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5474R-FITC
Lokale Artikelnummer::
BOSSBS-5474R-FITC
Beschreibung:
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7083R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7083R-A350
Lokale Artikelnummer::
BOSSBS-7083R-A350
Beschreibung:
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12372R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12372R-A488
Lokale Artikelnummer::
BOSSBS-12372R-A488
Beschreibung:
MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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