Schwefeltrioxid-Pyridin-Komplex
Artikel-Nr:
(BOSSBS-8671R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8671R-A555
Lokale Artikelnummer::
BOSSBS-8671R-A555
Beschreibung:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6851R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6851R-A680
Lokale Artikelnummer::
BOSSBS-6851R-A680
Beschreibung:
The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3502R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3502R-HRP
Lokale Artikelnummer::
BOSSBS-3502R-HRP
Beschreibung:
Synapsin II is a member of the synapsin gene family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family is a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4038R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4038R-CY7
Lokale Artikelnummer::
BOSSBS-4038R-CY7
Beschreibung:
SLC25A13 is a member of the mitochondrial carrier family. It contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. It catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in the SLC25A13 gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2509R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2509R-A555
Lokale Artikelnummer::
BOSSBS-2509R-A555
Beschreibung:
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2509R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2509R-HRP
Lokale Artikelnummer::
BOSSBS-2509R-HRP
Beschreibung:
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6076R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6076R-A647
Lokale Artikelnummer::
BOSSBS-6076R-A647
Beschreibung:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6076R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6076R-A350
Lokale Artikelnummer::
BOSSBS-6076R-A350
Beschreibung:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6076R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6076R-A488
Lokale Artikelnummer::
BOSSBS-6076R-A488
Beschreibung:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7070R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7070R-A555
Lokale Artikelnummer::
BOSSBS-7070R-A555
Beschreibung:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7070R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7070R-FITC
Lokale Artikelnummer::
BOSSBS-7070R-FITC
Beschreibung:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9654R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9654R
Lokale Artikelnummer::
BOSSBS-9654R
Beschreibung:
14-3-3 are activates tyrosine and tryptophan hydroxylases in the presence of Ca (2+)/calmodulin-dependent protein kinase II, and strongly activates protein kinase C. Is probably a multifunctional regulator of the cell signaling processes mediated by both kinases. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It belongs to the 14-3-3 family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7070R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7070R-HRP
Lokale Artikelnummer::
BOSSBS-7070R-HRP
Beschreibung:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1907R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1907R-HRP
Lokale Artikelnummer::
BOSSBS-1907R-HRP
Beschreibung:
This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8869R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8869R-A488
Lokale Artikelnummer::
BOSSBS-8869R-A488
Beschreibung:
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7070R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7070R-A488
Lokale Artikelnummer::
BOSSBS-7070R-A488
Beschreibung:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
VE:
1 * 100 µl
Preis auf Anfrage
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