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[4-(2-Fluorophenoxy)phenyl]methanol
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[4-(2-Fluorophenoxy)phenyl]methanol
Artikel-Nr:
(BOSSBS-12460R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12460R
Lokale Artikelnummer::
BOSSBS-12460R
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13248R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-A647
Lokale Artikelnummer::
BOSSBS-13248R-A647
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1282R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1282R-A647
Lokale Artikelnummer::
BOSSBS-1282R-A647
Beschreibung:
iASPP (inhibitor of apoptosis stimulating protein of p53, RelA-associated inhibitor (RAI), NFKap B-interacting protein 1, protein phosphatase 1 regulatory subunit 13-like, PPP1R13L) is the third member of the ASPP family of proteins. Unlike ASPP1 and ASPP2, which interact with p53 and enhance its ability to induce apoptosis, iASPP inhibits apoptosis induced by p53 overexpression. iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA),3 interacts with NFKap B in vivo, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles. iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia. Alternate Names: apoptosis stimulating protein of P53 1; Apoptosis-stimulating of p53 protein 2; Tumor suppressor p53-binding protein 2; p53-binding protein 2; p53BP2; 53BP2; Bcl2-binding protein; Bbp; Renal carcinoma antigen NY-REN-51.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13248R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-A350
Lokale Artikelnummer::
BOSSBS-13248R-A350
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI3529P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3529P
Lokale Artikelnummer::
PRSI3529P
Beschreibung:
SARS matrix peptide is used for blocking the activity of the SARS matrix antibody.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1282R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1282R-CY5.5
Lokale Artikelnummer::
BOSSBS-1282R-CY5.5
Beschreibung:
iASPP (inhibitor of apoptosis stimulating protein of p53, RelA-associated inhibitor (RAI), NFKap B-interacting protein 1, protein phosphatase 1 regulatory subunit 13-like, PPP1R13L) is the third member of the ASPP family of proteins. Unlike ASPP1 and ASPP2, which interact with p53 and enhance its ability to induce apoptosis, iASPP inhibits apoptosis induced by p53 overexpression. iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA),3 interacts with NFKap B in vivo, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles. iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia. Alternate Names: apoptosis stimulating protein of P53 1; Apoptosis-stimulating of p53 protein 2; Tumor suppressor p53-binding protein 2; p53-binding protein 2; p53BP2; 53BP2; Bcl2-binding protein; Bbp; Renal carcinoma antigen NY-REN-51.
VE:
1 * 100 µl
Artikel-Nr:
(MAYBCC01601.250)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
CC01601.250
Lokale Artikelnummer::
MAYBCC01601.250
Beschreibung:
Piperonylsäure
VE:
1 * 250 mg
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ABNOMAB2222)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB2222
Lokale Artikelnummer::
ABNOMAB2222
Beschreibung:
Mouse monoclonal antibody raised against Disopyramide.
VE:
1 * 100 µG
Artikel-Nr:
(ABNOMAB2221)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB2221
Lokale Artikelnummer::
ABNOMAB2221
Beschreibung:
Mouse monoclonal antibody raised against Disopyramide.
VE:
1 * 100 µG
Artikel-Nr:
(KRAF13355.1700)
Lieferant:
Bernd Kraft
Hersteller-Artikelnummer::
13355.1700
Lokale Artikelnummer::
KRAF13355.1700
Beschreibung:
Pararosaniliniumchlorid Reagent R Reag. Ph. Eur.
VE:
1 * 250 mL
Artikel-Nr:
(SIALD2388-100MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
D2388-100MG
Lokale Artikelnummer::
SIALD2388-100MG
Beschreibung:
Cross-linking reagent
VE:
1 * 100 mg
Artikel-Nr:
(KGWA78212669)
Lieferant:
KGW
Hersteller-Artikelnummer::
78212669
Lokale Artikelnummer::
KGWA78212669
Beschreibung:
Dewargefäße und Kryolagerbehälter, Safety valve, 1,3 bar
VE:
1 * 1 ST
Lieferant:
Bohlender
Beschreibung:
Ideal zum Ablängen von Kapillaren und elastischen Schläuchen ohne Armierung.
Artikel-Nr:
(ABNOMAB5825)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB5825
Lokale Artikelnummer::
ABNOMAB5825
Beschreibung:
Mouse monoclonal antibody raised against H2-D2.
VE:
1 * 100 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
Dimethyl-3-oxoglutarat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-1282R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1282R-FITC
Lokale Artikelnummer::
BOSSBS-1282R-FITC
Beschreibung:
iASPP (inhibitor of apoptosis stimulating protein of p53, RelA-associated inhibitor (RAI), NFKap B-interacting protein 1, protein phosphatase 1 regulatory subunit 13-like, PPP1R13L) is the third member of the ASPP family of proteins. Unlike ASPP1 and ASPP2, which interact with p53 and enhance its ability to induce apoptosis, iASPP inhibits apoptosis induced by p53 overexpression. iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA),3 interacts with NFKap B in vivo, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles. iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia. Alternate Names: apoptosis stimulating protein of P53 1; Apoptosis-stimulating of p53 protein 2; Tumor suppressor p53-binding protein 2; p53-binding protein 2; p53BP2; 53BP2; Bcl2-binding protein; Bbp; Renal carcinoma antigen NY-REN-51.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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