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Methyl+3-bromo-2-chloro-6-fluorobenzoate
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Methyl+3-bromo-2-chloro-6-fluorobenzoate
Artikel-Nr:
(SIALC8474-1EA)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
C8474-1EA
Lokale Artikelnummer::
SIALC8474-1EA
Beschreibung:
Solar powered calculator with protective sliding case.
VE:
1 * 1 ST
Lieferant:
MP Biomedicals
Beschreibung:
This product is soluble in water (100 mg/ml), yielding a clear, colourless solution. The maximum solubility in water has been reported to be 1 g/0,6 ml. Soluble in 10% aqueous solution (clear, colourless solution).
Artikel-Nr:
(BOSSBS-3242R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3242R-HRP
Lokale Artikelnummer::
BOSSBS-3242R-HRP
Beschreibung:
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3730R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3730R-HRP
Lokale Artikelnummer::
BOSSBS-3730R-HRP
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Artikel-Nr:
(HEWLG6500-60701)
Lieferant:
Agilent
Hersteller-Artikelnummer::
G6500-60701
Lokale Artikelnummer::
HEWLG6500-60701
Beschreibung:
These are the supplies you need for your Markes Thermal Desorber.
VE:
1 * 1 ST
Lieferant:
HOEFER ELECTROPHORESIS
Beschreibung:
Das vertikale Mini-Elektrophoresesystem SE250 Mighty Small II wurde speziell für schnelles Screening und schnelle elektrophoretische Trennung konzipiert.
Artikel-Nr:
(PRSI27-035)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-035
Lokale Artikelnummer::
PRSI27-035
Beschreibung:
Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4, but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II.Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI76-383)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-383
Lokale Artikelnummer::
PRSI76-383
Beschreibung:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI76-372)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-372
Lokale Artikelnummer::
PRSI76-372
Beschreibung:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI26-892)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-892
Lokale Artikelnummer::
PRSI26-892
Beschreibung:
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. ARG2 (type II isoform) is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(HONC72186-25KG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
72186-25KG
Lokale Artikelnummer::
HONC72186-25KG
Beschreibung:
Zinkchlorid, Spezialqualität
VE:
1 * 25 kg
Lieferant:
Tonbo Biosciences
Beschreibung:
The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247). The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).
Artikel-Nr:
(PRSI28-570)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-570
Lokale Artikelnummer::
PRSI28-570
Beschreibung:
C2ta is essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
Zinkstearat, Sigma-Aldrich®
Artikel-Nr:
(SIAL379816-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
379816-1G
Lokale Artikelnummer::
SIAL379816-1G
Beschreibung:
Dikaliumtetrachloropalladat, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(USBI150150)
Lieferant:
US Biological
Hersteller-Artikelnummer::
150150
Lokale Artikelnummer::
USBI150150
Beschreibung:
Anti-XRCC5 Goat Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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