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b-Amino-4-bromobenzeneethanol
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b-Amino-4-bromobenzeneethanol
Lieferant:
Thermo Scientific
Beschreibung:
Appearance: White to light beige Crystalline powder
Artikel-Nr:
(BOSSBS-12332R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12332R-CY7
Lokale Artikelnummer::
BOSSBS-12332R-CY7
Beschreibung:
Dyrk is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis (1–3). Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation (1). Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4). Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions (4). Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome (1,5). Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4). Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland (1). The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively (4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12332R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12332R
Lokale Artikelnummer::
BOSSBS-12332R
Beschreibung:
Dyrk is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis (1–3). Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation (1). Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4). Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions (4). Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome (1,5). Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4). Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland (1). The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively (4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12323R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12323R-A350
Lokale Artikelnummer::
BOSSBS-12323R-A350
Beschreibung:
Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells. CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch. The human protein contains 1,225 amino acid residues and shares significant homology with the domain structures of the rat protein.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Indo-1, AM ester is membrane-permeant and thus can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate cell loading. Indo-1-AM Ester itself does not bind Ca2+ , but it is readily hydrolyzed to indo-1 by endogenous esterases once it enters cells.
Artikel-Nr:
(APOSOR14679-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR14679-5G
Lokale Artikelnummer::
APOSOR14679-5G
Beschreibung:
(1S,3R)-N-Boc-1-aminocyclopentane-3-carboxylic acid 95+%
VE:
1 * 5 g
Lieferant:
Merck
Beschreibung:
Xylenolorange Tetranatriumsalz, Supelco®
Lieferant:
Alfa Aesar
Beschreibung:
2,4-Dichlor-6-iodanilin ≥97%
Artikel-Nr:
(H63170.03)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
H63170.03
Lokale Artikelnummer::
ALFAH63170.03
Beschreibung:
Fmoc-N-Me-Thr(tBu)-OH 99%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5,6-Dihydro-4H-cyclopenta[d][1,3]thiazol-2-amine
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(±)-2-Azabicyclo[2.2.1]hept-5-en-3-on 97+%
Artikel-Nr:
(APOSOR960889-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR960889-25G
Lokale Artikelnummer::
APOSOR960889-25G
Beschreibung:
N-(tert-Butoxycarbonyl)-N-methyl-D-alanine 97%
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-11533R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11533R-CY5
Lokale Artikelnummer::
BOSSBS-11533R-CY5
Beschreibung:
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM1214-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1214-50
Lokale Artikelnummer::
BTIUBNUM1214-50
Beschreibung:
Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-6659R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6659R-A750
Lokale Artikelnummer::
BOSSBS-6659R-A750
Beschreibung:
Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarised intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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