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beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
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beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
Artikel-Nr:
(BOSSBS-0787R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0787R-A555
Lokale Artikelnummer::
BOSSBS-0787R-A555
Beschreibung:
Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC â… molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0787R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0787R-A350
Lokale Artikelnummer::
BOSSBS-0787R-A350
Beschreibung:
Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC â… molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3234R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3234R-A350
Lokale Artikelnummer::
BOSSBS-3234R-A350
Beschreibung:
Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3234R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3234R-A555
Lokale Artikelnummer::
BOSSBS-3234R-A555
Beschreibung:
Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3234R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3234R-CY3
Lokale Artikelnummer::
BOSSBS-3234R-CY3
Beschreibung:
Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3236R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3236R-A647
Lokale Artikelnummer::
BOSSBS-3236R-A647
Beschreibung:
Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3236R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3236R-A488
Lokale Artikelnummer::
BOSSBS-3236R-A488
Beschreibung:
Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12543R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12543R-A680
Lokale Artikelnummer::
BOSSBS-12543R-A680
Beschreibung:
Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12418R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12418R-A750
Lokale Artikelnummer::
BOSSBS-12418R-A750
Beschreibung:
BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta Signalling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4117R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4117R-CY5
Lokale Artikelnummer::
BOSSBS-4117R-CY5
Beschreibung:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13148R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13148R-A555
Lokale Artikelnummer::
BOSSBS-13148R-A555
Beschreibung:
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), a subunit of MNSF, which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner. MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36% sequence identity with ubiquitin. This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3'-Aminoacetophenon
Artikel-Nr:
(BOSSBS-4286R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4286R-A350
Lokale Artikelnummer::
BOSSBS-4286R-A350
Beschreibung:
Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5347R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5347R-FITC
Lokale Artikelnummer::
BOSSBS-5347R-FITC
Beschreibung:
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq].eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB208247-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB208247-100
Lokale Artikelnummer::
ABCAAB208247-100
Beschreibung:
Anti-Fibrinopeptide B+Fibrinogen beta chain Rabbit Monoclonal Antibody [clone: EPR3083] (Alexa Fluor® 488)
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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