Suche >
beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
Drucken
Sie suchten nach:
107 546 results were found
beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
Artikel-Nr:
(BOSSBS-0758R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0758R-A350
Lokale Artikelnummer::
BOSSBS-0758R-A350
Beschreibung:
Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0758R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0758R-CY3
Lokale Artikelnummer::
BOSSBS-0758R-CY3
Beschreibung:
Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3341R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3341R-A488
Lokale Artikelnummer::
BOSSBS-3341R-A488
Beschreibung:
Phospholipase C is a key enzyme in phosphatidylinositol (PIP2) metabolism and lipid signaling pathways. The Phospholipase C family consists of 13 isozymes split between six subfamilies. Phospholipase C beta is activated by G protein subunits.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Nicotinsäure (Niacin)
Artikel-Nr:
(ABCAAB224391-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB224391-100
Lokale Artikelnummer::
ABCAAB224391-100
Beschreibung:
Anti-GATAD2B Rabbit Polyclonal Antibody
VE:
1 * 100 µl
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ABCAAB232832-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB232832-100
Lokale Artikelnummer::
ABCAAB232832-100
Beschreibung:
Anti-CRYBB2 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-3327R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3327R-HRP
Lokale Artikelnummer::
BOSSBS-3327R-HRP
Beschreibung:
Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2 and RPS6KA3), cyclic AMP-dependent protein kinase (PRKACA), protein kinase C (PRKCD and PRKCZ), serum and glucocorticoid-inducible kinase (SGK1, SGK2 and SGK3), p21-activated kinase-1 (PAK1), protein kinase PKN (PKN1 and PKN2). Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well as glucose and amino acid uptake and storage. Negatively regulates the TGF-beta-induced signaling by: modulating the association of SMAD3 and SMAD7 with TGF-beta receptor, phosphorylating SMAD2, SMAD3, SMAD4 and SMAD7, preventing the nuclear translocation of SMAD3 and SMAD4 and the translocation of SMAD7 from the nucleus to the cytoplasm in response to TGF-beta. Activates PPARG transcriptional activity and promotes adipocyte differentiation. Activates the NF-kappa-B pathway via phosphorylation of IKKB. The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II. Controls proliferation, survival, and growth of developing pancreatic cells. Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells. Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis. Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response. Plays an important role during thymocyte development by regulating the expression of key nutrient receptors on the surface of pre-T cells and mediating Notch-induced cell growth and proliferative responses.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,5-Anhydro-β-D-xylofuranose ≥97%
Artikel-Nr:
(BOSSBS-5774R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5774R-CY5.5
Lokale Artikelnummer::
BOSSBS-5774R-CY5.5
Beschreibung:
The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin, also known as ADSF) is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Fluoro-4-nitrophenyl 2-azido-2-deoxy-β-D-galactopyranoside 95%
Artikel-Nr:
(ABGEAP7935A)
Lieferant:
Abgent
Hersteller-Artikelnummer::
AP7935A
Lokale Artikelnummer::
ABGEAP7935A
Beschreibung:
Anti-PKNB Rabbit Polyclonal Antibody
VE:
1 * 400 µl
Artikel-Nr:
(BOSSBS-12864R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12864R
Lokale Artikelnummer::
BOSSBS-12864R
Beschreibung:
Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression.
VE:
1 * 100 µl
Artikel-Nr:
(USBIA0906-95G)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A0906-95G
Lokale Artikelnummer::
USBIA0906-95G
Beschreibung:
Anti-ADRBK1 Sheep Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBIT8250-31C)
Lieferant:
US Biological
Hersteller-Artikelnummer::
T8250-31C
Lokale Artikelnummer::
USBIT8250-31C
Beschreibung:
Anti-TGFBR1 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-0498R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0498R-CY5
Lokale Artikelnummer::
BOSSBS-0498R-CY5
Beschreibung:
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Bromo-4-chloro-3-indolyl N-acetyl-β-D-galactosaminide
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
