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cis-6-Amino-cyclohex-3-enecarboxylic+acid
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cis-6-Amino-cyclohex-3-enecarboxylic+acid
Artikel-Nr:
(BOSSBS-13223R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13223R-A750
Lokale Artikelnummer::
BOSSBS-13223R-A750
Beschreibung:
Fused toes protein homolog (FTS), also known as AKT-interacting protein (AKTIP) and Ft1, is a 292 amino acid protein that localizes to the cytoplasm and the cell membrane. A member of the ubiquitin-conjugating enzyme family, FTS binds directly to AKT1 to regulate apoptosis in a cell population. AKT1 is a protein that plays a critical role in a number of cellular responses, such as cell growth, protein synthesis, and antiapoptotic signaling. The interaction of FTS and AKT1 enhances the phosphorylation and activation of AKT1, which, through an AKT1/GSK-3/NFATc1 signaling cascade, results in the increased production of the proapoptotic hormone Fas ligand and thus an increase in apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5620R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5620R-FITC
Lokale Artikelnummer::
BOSSBS-5620R-FITC
Beschreibung:
Stat 5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9652R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9652R-A488
Lokale Artikelnummer::
BOSSBS-9652R-A488
Beschreibung:
C18orf1 is a 306 amino acid single-pass membrane protein that contains one LDL-receptor class A domain and belongs to the PMEPA1 family. C18orf1 exists as five alternatively spliced isoforms that display selective expression and are encoded by a gene that maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11413R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11413R-FITC
Lokale Artikelnummer::
BOSSBS-11413R-FITC
Beschreibung:
TSKS is a 592 amino acid protein that is highly expressed in human testicular tissue. Low levels of TSKS are detectable in prostate, placenta, fetal liver, thymus, and mammary gland tissues. TSKS is found to be downregulated in cancerous testicular tissue from seminoma, teratocarcinoma, embryonal and Leydig cell tumors concurrently with high expression in neighboring premalignant carcinoma. TSKS protein contains an N-terminal signal peptide, but does not contain a transmembrane region. TSKS has many potential phosphorylation and glycosylation sites and is phosphorylated by soluble recombinant TSSK2 in vitro. It is thought that TSKS likely plays a physiological role in spermatogenesis or spermiogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9053R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9053R-CY7
Lokale Artikelnummer::
BOSSBS-9053R-CY7
Beschreibung:
The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3’ region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3’ processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12337R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12337R
Lokale Artikelnummer::
BOSSBS-12337R
Beschreibung:
Emp is a 396 amino acid ubiquitously expressed adhesion protein. Expressed as 5 alternatively spliced isoforms, Emp contains one CTLH domain and one LisH domain. Emp can form a complex with F-actin, which is involved regulating actin distribution in erythroblasts and macrophages. Considered to assist with cell division and nuclear architecture, Emp is localized with condensed chromatin at prophase, nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis. Although the exact function of Emp is unknown, Emp is suggested to be involvement in erythroblast-macrophage cell attachment, terminal maturation and enucleation of erythroid cells, and inhibiting apoptosis of erythroblasts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9477R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9477R-HRP
Lokale Artikelnummer::
BOSSBS-9477R-HRP
Beschreibung:
May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.Myomegalin, is a 2,346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5371R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5371R-HRP
Lokale Artikelnummer::
BOSSBS-5371R-HRP
Beschreibung:
PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12500R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12500R-A647
Lokale Artikelnummer::
BOSSBS-12500R-A647
Beschreibung:
The apolipoprotein L gene family maps to a region on chromosome 22 and encodes six highly homologous proteins designated apoL-I, apoL-II, apoL-III, apoL-IV, apoL-V and apoL-VI, all of which function as components of plasma lipoproteins. ApoL-V (apolipoprotein L-V), also known as APOL5, is a 433 amino acid protein that localizes to the cytoplasm and belongs to the apolipoprotein L family. Expressed in a variety of tissues including testis, stomach, uterus and skeletal muscle, apoL-V is thought to affect the movement of lipids in the cytoplasm and may allow the binding of lipids to organelles. Like other members of the apolipoprotein L family, apoL-V is thought to be involved in the development of schizophrenia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12337R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12337R-CY3
Lokale Artikelnummer::
BOSSBS-12337R-CY3
Beschreibung:
Emp is a 396 amino acid ubiquitously expressed adhesion protein. Expressed as 5 alternatively spliced isoforms, Emp contains one CTLH domain and one LisH domain. Emp can form a complex with F-actin, which is involved regulating actin distribution in erythroblasts and macrophages. Considered to assist with cell division and nuclear architecture, Emp is localized with condensed chromatin at prophase, nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis. Although the exact function of Emp is unknown, Emp is suggested to be involvement in erythroblast-macrophage cell attachment, terminal maturation and enucleation of erythroid cells, and inhibiting apoptosis of erythroblasts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12177R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12177R-A350
Lokale Artikelnummer::
BOSSBS-12177R-A350
Beschreibung:
Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12302R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12302R-A647
Lokale Artikelnummer::
BOSSBS-12302R-A647
Beschreibung:
PHC1 is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9032R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9032R-A555
Lokale Artikelnummer::
BOSSBS-9032R-A555
Beschreibung:
MAWDBP (MAWD binding protein), also known as PBLD (phenazine biosynthesis-like protein domain containing) or MAWBP, is a 288 amino acid protein that belongs to the phenazine biosynthesis-like protein (PhzF) family. It has been suggested that MAWDBP is the only representative of the PhzF family in the human genome. Expressed in most tissues, MAWDBP is a WD-40 repeat-containing β-propeller protein believed to participate in the MAPK signaling pathway. Involved in multiple basic cellular functions, expression of MAWDBP is elevated in several disease processes, including insulin resistance, folate deficiency and hypotension. It is thought that MAWDBP may also be involved in carcinogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11864R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11864R-A750
Lokale Artikelnummer::
BOSSBS-11864R-A750
Beschreibung:
NEPH2 is a 778 amino acid single-pass type I membrane protein that belongs to the nephrin-like protein family and immunoglobulin superfamily. Expressed in both fetal and adult brain, as well as podocytes of kidney glomeruli, NEPH2 contains five Ig-like C2-type (immunoglobulin-like) domains and is thought to play a role in the hematopoetic supportive capacity of stroma cells. NEPH2 undergoes alternative splicing to produce two isoforms and contains a C-terminal cytoplasmic domain which it uses to interact with Podocin, a podocyte protein involved in ultrafiltration. Defects in the gene encoding NEPH2 are associated with mental retardation autosomal dominant type 4 (MRD4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9723R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9723R-A680
Lokale Artikelnummer::
BOSSBS-9723R-A680
Beschreibung:
The human augmin complex (HAUS) is an evolutionarily conserved 8-subunit protein complex that was initially discovered in Drosophila. The HAUS complex is essential for microtubule generation, centrosome integrity, mitotic spindle assembly and completion of cytokinesis. HAUS6 (HAUS augmin-like complex, subunit 6), also known as FAM29A or Dgt6, is a 955 amino acid component of the augmin complex. Required for mitotic progression, HAUS6 localizes to cytoplasm, cytoskeleton, mitotic spindle microtubules and interphase centrosomes, and undergoes post-translational phosphorylation following mitosis on multiple serine and threonine residues. HAUS6 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 9.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12500R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12500R-CY5
Lokale Artikelnummer::
BOSSBS-12500R-CY5
Beschreibung:
The apolipoprotein L gene family maps to a region on chromosome 22 and encodes six highly homologous proteins designated apoL-I, apoL-II, apoL-III, apoL-IV, apoL-V and apoL-VI, all of which function as components of plasma lipoproteins. ApoL-V (apolipoprotein L-V), also known as APOL5, is a 433 amino acid protein that localizes to the cytoplasm and belongs to the apolipoprotein L family. Expressed in a variety of tissues including testis, stomach, uterus and skeletal muscle, apoL-V is thought to affect the movement of lipids in the cytoplasm and may allow the binding of lipids to organelles. Like other members of the apolipoprotein L family, apoL-V is thought to be involved in the development of schizophrenia.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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