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n-Butyl+phosphate
Artikel-Nr:
(PRSI79-132)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-132
Lokale Artikelnummer::
PRSI79-132
Beschreibung:
Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3, 4, 5-trisphosphate, phosphatidylinositol 3, 4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3, 4, 5)P3 > PtdIns(3, 4)P2 > PtdIns3P > Ins(1, 3, 4, 5)P4. The lipid phosphatase activity is critical for its tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation. Dephosphorylates tyrosine-phosphorylated focal adhesion kinase and inhibits cell migration and integrin-mediated cell spreading and focal adhesion formation. May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue.
VE:
1 * 100 µG
Lieferant:
Spectrum Chemical
Beschreibung:
Ammonium Phosphate Dibasic, FCC is a food ingredient used as an acidity regulator and raising agent. It is listed on the FDA's Generally Recognized As Safe (GRAS) list of substances. Spectrum Chemical offers over 300 Food Grade (FCC) chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Artikel-Nr:
(BOSSBS-1535R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1535R-CY5
Lokale Artikelnummer::
BOSSBS-1535R-CY5
Beschreibung:
Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1535R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1535R-A350
Lokale Artikelnummer::
BOSSBS-1535R-A350
Beschreibung:
Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13016R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13016R-A647
Lokale Artikelnummer::
BOSSBS-13016R-A647
Beschreibung:
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
VE:
1 * 100 µl
Artikel-Nr:
(REST31903)
Lieferant:
Restek
Hersteller-Artikelnummer::
31903
Lokale Artikelnummer::
REST31903
Beschreibung:
Consists of 47 components, those are acenaphthene, acenaphthylene, acetophenone, anthracene, benzanthracene, benzopyrene, benzofluoranthene, benzoperylene, benzofluoranthene, benzyl butyl phthalate, biphenyl, bismethane, bisether, bisphthalate, 4-bromophenyl phenyl ether, carbazole, 4-chloroaniline, 2-chloronaphthalene, 4-chlorophenyl phenyl ether, chrysene, dibenzanthracene, dibenzofuran, diethylphthalate, dimethylphthalate, di-n-butyl phthalate, 2,4-dinitrotoluene, 2,6-dinitrotoluene, di-n-octyl phthalate, diphenylamine *,fluoranthene, fluorene, hexachlorobenzene, hexachloro-1,3-butadiene , hexachlorocyclopentadiene, hexachloroethane, indenopyrene, isophorone, 2-methylnaphthalene, naphthalene, 2-nitroaniline, 3-nitroaniline, 4-nitroaniline, nitrobenzene, n-nitroso-di-n-propylamine, 2,2'-oxybis, phenanthrene and pyrene.
VE:
1 * 1 Ampull
Artikel-Nr:
(REST33227)
Lieferant:
Restek
Hersteller-Artikelnummer::
33227
Lokale Artikelnummer::
REST33227
Beschreibung:
The mixture consists of benzyl butyl phthalate, bisphthalate, bisphthalate, bisphthalate, bisphthalate, bisphthalate, di-n-butylphthalate, diethylphthalate, di-n-hexyl phthalate, dimethylphthalate, di-nonyl phthalate, di-n-octyl phthalate, dipentylphthalate, phthalic acid dicyclohexyl ester, phthalic acid diisobutyl ester.
VE:
1 * 1 Ampull
Artikel-Nr:
(BOSSBS-1437R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1437R-FITC
Lokale Artikelnummer::
BOSSBS-1437R-FITC
Beschreibung:
MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3398R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3398R-CY5.5
Lokale Artikelnummer::
BOSSBS-3398R-CY5.5
Beschreibung:
SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3398R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3398R-CY7
Lokale Artikelnummer::
BOSSBS-3398R-CY7
Beschreibung:
SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3037R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3037R-A680
Lokale Artikelnummer::
BOSSBS-3037R-A680
Beschreibung:
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyses the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3398R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3398R-A680
Lokale Artikelnummer::
BOSSBS-3398R-A680
Beschreibung:
SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyses the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3398R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3398R-A488
Lokale Artikelnummer::
BOSSBS-3398R-A488
Beschreibung:
SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3929R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3929R-A350
Lokale Artikelnummer::
BOSSBS-3929R-A350
Beschreibung:
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3929R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3929R-A555
Lokale Artikelnummer::
BOSSBS-3929R-A555
Beschreibung:
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3398R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3398R-HRP
Lokale Artikelnummer::
BOSSBS-3398R-HRP
Beschreibung:
SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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