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3-(Difluoromethyl)benzoic+acid
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3-(Difluoromethyl)benzoic+acid
Artikel-Nr:
(BLDPBD83645-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD83645-1G
Lokale Artikelnummer::
BLDPBD83645-1G
Beschreibung:
3-Amino-1,1,1-trifluoropropan-2-ol 96%
VE:
1 * 1 g
Lieferant:
Sigma-Aldrich
Beschreibung:
(R)-(+)-α-Methylbenzylamin, Sigma-Aldrich®
Artikel-Nr:
(SIAL77880-10ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
77880-10ML
Lokale Artikelnummer::
SIAL77880-10ML
Beschreibung:
(R)-(+)-α-Methylbenzylamin, Sigma-Aldrich®
VE:
1 * 10 mL
Artikel-Nr:
(BOSSBS-2803R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2803R-CY5
Lokale Artikelnummer::
BOSSBS-2803R-CY5
Beschreibung:
Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2803R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2803R-A680
Lokale Artikelnummer::
BOSSBS-2803R-A680
Beschreibung:
Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyses the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2803R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2803R-CY7
Lokale Artikelnummer::
BOSSBS-2803R-CY7
Beschreibung:
Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
2-Methyl-3-pyridinol ≥99%
Artikel-Nr:
(BLDPBD99215-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD99215-250MG
Lokale Artikelnummer::
BLDPBD99215-250MG
Beschreibung:
4-Morpholin-4-yl-1,2,5-thiadiazol-3-ol 95%
VE:
1 * 250 mg
Artikel-Nr:
(442539.)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
442539
Lokale Artikelnummer::
SUPL442539
Beschreibung:
1-Decanol analytischer Standard, Supelco®
VE:
1 * 1 ST
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-(tert-Butyl)-6-(chloromethyl)pyrimidin-4-ol
Lieferant:
Merck
Beschreibung:
(1S)-(-)-Borneol zur Synthese, Sigma-Aldrich®
Artikel-Nr:
(SIALB5936-200UL)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
B5936-200UL
Lokale Artikelnummer::
SIALB5936-200UL
Beschreibung:
Brefeldin A produced from <i>Penicillium brefeldianum</i> may be used to study protein and lipid transport between Golgi complex and the cell surface.
VE:
1 * 200 µl
Artikel-Nr:
(APOSOR480291-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR480291-1G
Lokale Artikelnummer::
APOSOR480291-1G
Beschreibung:
(2S)-1-(1H-1,2,4-Triazol-1-yl)propan-2-ol 95%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(1S)-(+)-2-Amino-1-phenylethan-1-ol hemihydrate
Artikel-Nr:
(APOSPC300876-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC300876-1G
Lokale Artikelnummer::
APOSPC300876-1G
Beschreibung:
3-[(4-Chlorobenzyl)amino]-1,1,1-trifluoropropan-2-ol
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1H,1H-Nonafluoro-3,6-dioxaheptan-1-ol
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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