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2-Fluoro-3-pyridineboronic acid
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2-Fluoro-3-pyridineboronic acid
Artikel-Nr:
(BOSSBS-7689R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7689R-A488
Lokale Artikelnummer::
BOSSBS-7689R-A488
Beschreibung:
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
VE:
1 * 100 µl
Artikel-Nr:
(CRM498-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
CRM498-100G
Lokale Artikelnummer::
SUPLCRM498-100G
Beschreibung:
pH/Conductivity CRM - clay soil, Supelco®
VE:
1 * 100 g
Lieferant:
Alfa Aesar
Beschreibung:
Stab. with potassium carbonate
Artikel-Nr:
(BOSSBS-17067R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-17067R-HRP
Lokale Artikelnummer::
BOSSBS-17067R-HRP
Beschreibung:
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3034R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3034R-CY7
Lokale Artikelnummer::
BOSSBS-3034R-CY7
Beschreibung:
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5402R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5402R-CY3
Lokale Artikelnummer::
BOSSBS-5402R-CY3
Beschreibung:
KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5402R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5402R-CY7
Lokale Artikelnummer::
BOSSBS-5402R-CY7
Beschreibung:
KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Cyanimidodithiocarbonic acidmonomethyl ester monopotassium salt 95%
Lieferant:
Alfa Aesar
Beschreibung:
Stab. with 0.1% potassium hydroxide
Artikel-Nr:
(BOSSBS-3034R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3034R-A488
Lokale Artikelnummer::
BOSSBS-3034R-A488
Beschreibung:
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6760R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6760R-A647
Lokale Artikelnummer::
BOSSBS-6760R-A647
Beschreibung:
Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Clavulanate:Cellulose
Artikel-Nr:
(BOSSBS-5403R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5403R-A555
Lokale Artikelnummer::
BOSSBS-5403R-A555
Beschreibung:
KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5403R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5403R-HRP
Lokale Artikelnummer::
BOSSBS-5403R-HRP
Beschreibung:
KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11728R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11728R-CY7
Lokale Artikelnummer::
BOSSBS-11728R-CY7
Beschreibung:
Epilepsy affects about 0.5% of the world’s population and has a large genetic component. Epilepsy results from an electrical hyperexcitability in the central nervous system. Potassium channels are important regulators of electrical signaling, determining the firing properties and responsiveness of a variety of neurons. Benign familial neonatal convulsions (BFNC), an autosomal dominant epilepsy of infancy, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes. KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains. Both proteins display a broad distribution within the brain, with expression patterns that largely overlap.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11728R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11728R-A350
Lokale Artikelnummer::
BOSSBS-11728R-A350
Beschreibung:
Epilepsy affects about 0.5% of the world’s population and has a large genetic component. Epilepsy results from an electrical hyperexcitability in the central nervous system. Potassium channels are important regulators of electrical signaling, determining the firing properties and responsiveness of a variety of neurons. Benign familial neonatal convulsions (BFNC), an autosomal dominant epilepsy of infancy, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes. KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains. Both proteins display a broad distribution within the brain, with expression patterns that largely overlap.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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