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ligase
Artikel-Nr:
(BOSSBS-8048R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8048R-A350
Lokale Artikelnummer::
BOSSBS-8048R-A350
Beschreibung:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1212R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1212R-A750
Lokale Artikelnummer::
BOSSBS-1212R-A750
Beschreibung:
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1212R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1212R-CY7
Lokale Artikelnummer::
BOSSBS-1212R-CY7
Beschreibung:
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1212R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1212R-CY3
Lokale Artikelnummer::
BOSSBS-1212R-CY3
Beschreibung:
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7807R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7807R-HRP
Lokale Artikelnummer::
BOSSBS-7807R-HRP
Beschreibung:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for cell division. BCR E3 ubiquitin ligase complexes mediate the ubiquitination of target proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7807R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7807R-FITC
Lokale Artikelnummer::
BOSSBS-7807R-FITC
Beschreibung:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for cell division. BCR E3 ubiquitin ligase complexes mediate the ubiquitination of target proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7807R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7807R-A647
Lokale Artikelnummer::
BOSSBS-7807R-A647
Beschreibung:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for cell division. BCR E3 ubiquitin ligase complexes mediate the ubiquitination of target proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1212R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1212R-A350
Lokale Artikelnummer::
BOSSBS-1212R-A350
Beschreibung:
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6523R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6523R-CY5.5
Lokale Artikelnummer::
BOSSBS-6523R-CY5.5
Beschreibung:
DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas.Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12394R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12394R-A555
Lokale Artikelnummer::
BOSSBS-12394R-A555
Beschreibung:
DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context; mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12394R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12394R-A488
Lokale Artikelnummer::
BOSSBS-12394R-A488
Beschreibung:
DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context; mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6523R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6523R-A488
Lokale Artikelnummer::
BOSSBS-6523R-A488
Beschreibung:
DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas.Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6523R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6523R-A555
Lokale Artikelnummer::
BOSSBS-6523R-A555
Beschreibung:
DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas.Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8376R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8376R-CY3
Lokale Artikelnummer::
BOSSBS-8376R-CY3
Beschreibung:
RNF160 may function as an E3 ubiquitin-protein ligase. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9338R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9338R-CY3
Lokale Artikelnummer::
BOSSBS-9338R-CY3
Beschreibung:
MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9291R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9291R-A750
Lokale Artikelnummer::
BOSSBS-9291R-A750
Beschreibung:
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localisation. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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