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DR+WEIGERT
Artikel-Nr:
(BOSSBS-9232R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9232R-A647
Lokale Artikelnummer::
BOSSBS-9232R-A647
Beschreibung:
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9232R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9232R-A350
Lokale Artikelnummer::
BOSSBS-9232R-A350
Beschreibung:
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9254R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9254R-FITC
Lokale Artikelnummer::
BOSSBS-9254R-FITC
Beschreibung:
E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12482R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12482R-A647
Lokale Artikelnummer::
BOSSBS-12482R-A647
Beschreibung:
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5174R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5174R-A647
Lokale Artikelnummer::
BOSSBS-5174R-A647
Beschreibung:
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5174R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5174R-A350
Lokale Artikelnummer::
BOSSBS-5174R-A350
Beschreibung:
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10059R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10059R-A350
Lokale Artikelnummer::
BOSSBS-10059R-A350
Beschreibung:
Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9225R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9225R-CY7
Lokale Artikelnummer::
BOSSBS-9225R-CY7
Beschreibung:
Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9290R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9290R-CY5.5
Lokale Artikelnummer::
BOSSBS-9290R-CY5.5
Beschreibung:
PJA2, also known as E3 ubiquitin-protein ligase praja-2, RNF131 (ring finger protein 131) or Neurodap1, is a 708 amino acid protein that contains one ring-type zinc finger and exists as two alternatively spliced isoforms. Significantly conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PJA2 shares 52% identity with PJA1, which is involved in protein ubiquitination in brain and may play a role in X-linked mental retardation. Encoded by a gene that maps to human chromosome 5q21.3, PJA2 localizes to both endoplasmic reticulum and Golgi apparatus membranes. Participating in E2-dependent, E3 ubiquitin-protein ligase activity, PJA2 binds to a variety of E2s and interacts with ubiquitin-conjugating enzymes, such as UBE2D2, in vitro.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9628R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9628R-CY5
Lokale Artikelnummer::
BOSSBS-9628R-CY5
Beschreibung:
C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9121R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9121R
Lokale Artikelnummer::
BOSSBS-9121R
Beschreibung:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9628R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9628R
Lokale Artikelnummer::
BOSSBS-9628R
Beschreibung:
C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9628R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9628R-CY3
Lokale Artikelnummer::
BOSSBS-9628R-CY3
Beschreibung:
C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9120R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9120R
Lokale Artikelnummer::
BOSSBS-9120R
Beschreibung:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8383R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8383R-CY3
Lokale Artikelnummer::
BOSSBS-8383R-CY3
Beschreibung:
Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (UBE1s), ubiquitin-conjugating enzymes (UBE2s), and ubiquitin-protein ligases (UBE3s). When ubiquitin is activated by a UBE1, it is transferred to the cysteine residue on a UBE2. UBE2 then binds a UBE3, which transfers the ubiquitin from the UBE2 cysteine to a lysine residue on the target protein. Ubiquitin-conjugating enzyme E2 Q1 (UBE2Q1), also known as ubiquitin-protein ligase Q1 or ubiquitin carrier protein Q1, is an 422 amino acid protein belonging to the ubiquitin-conjugating enzyme (UBE2) family. Two named isoforms of UBE2Q1 exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9232R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9232R-A750
Lokale Artikelnummer::
BOSSBS-9232R-A750
Beschreibung:
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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