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ligase
Artikel-Nr:
(BOSSBS-11625R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11625R-FITC
Lokale Artikelnummer::
BOSSBS-11625R-FITC
Beschreibung:
WW domain-binding protein 2 (WBP2) is a 261 amino acid protein expressed in most tissues. The WW domain is composed of 38 to 40 semi-conserved amino acids and is shared by various groups of proteins, including structural, regulatory and signaling proteins. The domain mediates protein-protein interactions through the binding of polyproline ligands. WBP2 binds to the WW domain of Yes-associated protein (YAP), WW domain containing E3 ubiquitin protein ligase 1 (AIP5) and WW domain containing E3 ubiquitin protein ligase 2 (AIP2). The gene encoding WBP2 is located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3648R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3648R-A647
Lokale Artikelnummer::
BOSSBS-3648R-A647
Beschreibung:
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7778R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7778R-A750
Lokale Artikelnummer::
BOSSBS-7778R-A750
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13682R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13682R-CY3
Lokale Artikelnummer::
BOSSBS-13682R-CY3
Beschreibung:
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9141R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9141R-CY5
Lokale Artikelnummer::
BOSSBS-9141R-CY5
Beschreibung:
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7832R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7832R-A680
Lokale Artikelnummer::
BOSSBS-7832R-A680
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13682R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13682R-CY7
Lokale Artikelnummer::
BOSSBS-13682R-CY7
Beschreibung:
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12486R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12486R-A350
Lokale Artikelnummer::
BOSSBS-12486R-A350
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7832R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7832R-A647
Lokale Artikelnummer::
BOSSBS-7832R-A647
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9141R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9141R-CY7
Lokale Artikelnummer::
BOSSBS-9141R-CY7
Beschreibung:
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9141R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9141R-A488
Lokale Artikelnummer::
BOSSBS-9141R-A488
Beschreibung:
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9141R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9141R-FITC
Lokale Artikelnummer::
BOSSBS-9141R-FITC
Beschreibung:
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13682R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13682R-A350
Lokale Artikelnummer::
BOSSBS-13682R-A350
Beschreibung:
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13682R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13682R-A647
Lokale Artikelnummer::
BOSSBS-13682R-A647
Beschreibung:
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13682R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13682R-A555
Lokale Artikelnummer::
BOSSBS-13682R-A555
Beschreibung:
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7832R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7832R-HRP
Lokale Artikelnummer::
BOSSBS-7832R-HRP
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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