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Sulindac+sulphone-acyl-\u03B2-D-glucuronide
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Sulindac+sulphone-acyl-\u03B2-D-glucuronide
Artikel-Nr:
(PRSI31-165)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-165
Lokale Artikelnummer::
PRSI31-165
Beschreibung:
PGR is a member of the steroid receptor superfamily. The protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-576)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-576
Lokale Artikelnummer::
PRSI45-576
Beschreibung:
Anti-FBXL12 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-924)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-924
Lokale Artikelnummer::
PRSI27-924
Beschreibung:
TSC22D2 belongs to the TSC-22/Dip/Bun family and the function remains unknown.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-664)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-664
Lokale Artikelnummer::
PRSI28-664
Beschreibung:
TTC19's fucntion is not fully determined yet.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-413)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-413
Lokale Artikelnummer::
PRSI26-413
Beschreibung:
ATP10D is a multi-pass membrane protein. It belongs to the cation transport ATPase (P-type) family, type IV subfamily. The exact function of ATP10D remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-376)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-376
Lokale Artikelnummer::
PRSI91-376
Beschreibung:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7391)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7391
Lokale Artikelnummer::
PRSI7391
Beschreibung:
AKT1S1 Antibody: The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI60-863)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-863
Lokale Artikelnummer::
PRSI60-863
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI60-743)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-743
Lokale Artikelnummer::
PRSI60-743
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI92-656)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-656
Lokale Artikelnummer::
PRSI92-656
Beschreibung:
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumour immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIPM-4821)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
PM-4821
Lokale Artikelnummer::
PRSIPM-4821
Beschreibung:
Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI19-366)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-366
Lokale Artikelnummer::
PRSI19-366
Beschreibung:
Anti-CRTAP Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI29-720)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-720
Lokale Artikelnummer::
PRSI29-720
Beschreibung:
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult like. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 -alpha-2 -alpha-1 - theta1 - 3'.Zeta-globin (HBZ ) is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult like. The zeta-globin gene is a member of the human alpha-globin gene cluster that involves 4 functional genes and 3 nonfunctional pseudogenes. The order of genes is: 5'-zeta -- pseudozeta -- pseudoalpha2 -- pseudoalpha1 --alpha2 -- alph1 -- theta1-3'.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-527)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-527
Lokale Artikelnummer::
PRSI26-527
Beschreibung:
PHF12 acts as a transcriptional repressor. It is involved in recruitment of functional SIN3A complexes to DNA. PHF12 represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). IT may also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-518)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-518
Lokale Artikelnummer::
PRSI45-518
Beschreibung:
Anti-UBR5 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI49-331)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-331
Lokale Artikelnummer::
PRSI49-331
Beschreibung:
Cbl-c is also known as signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3, and RING finger protein 57. Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl-c (a.k.a. Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Cbl-c knock out mice show no obvious phenotype. Thus, the physiological role of Cbl-c is not known.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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