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BIOSS INC
Artikel-Nr:
(BOSSBS-6006R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6006R-A750
Lokale Artikelnummer::
BOSSBS-6006R-A750
Beschreibung:
FBXO31 belongs to the F-box protein family. Such proteins are characterised by an F-box motif of approximately 40 residues. F-box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains. There are two different isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9460R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9460R-A680
Lokale Artikelnummer::
BOSSBS-9460R-A680
Beschreibung:
Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bis-acetamide inducible 2 (HEXIM2) comprise a family of proteins which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK. P-TEFb is composed of a catalytic subunit, Cdk9, and either Cyclin T1 or T2 as a regulatory subunit. This complex regulates eukaryotic gene expression at the level of elongation. The C-terminal domains of HEXIM proteins interact directly with each other. Via these domains, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle. Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3398R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3398R-A350
Lokale Artikelnummer::
BOSSBS-3398R-A350
Beschreibung:
SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6804R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6804R-A680
Lokale Artikelnummer::
BOSSBS-6804R-A680
Beschreibung:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0598R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0598R-A350
Lokale Artikelnummer::
BOSSBS-0598R-A350
Beschreibung:
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11764R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11764R
Lokale Artikelnummer::
BOSSBS-11764R
Beschreibung:
OPA1 is a 120kDa protein belonging to the dynamin family. The OPA1 gene has been localized to 3q29. The gene is targeted to mitochondria and is involved in mitochondrial biogenesis. Defects in OPA1 are a cause of optic atrophy type 1. OPA1 is mostly expressed in retina but can also be expressed in brain, testis, heart and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1574R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1574R-A647
Lokale Artikelnummer::
BOSSBS-1574R-A647
Beschreibung:
Provides the precursors necessary for DNA synthesis. catalyses the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4295R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4295R-A750
Lokale Artikelnummer::
BOSSBS-4295R-A750
Beschreibung:
Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1449R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1449R-A488
Lokale Artikelnummer::
BOSSBS-1449R-A488
Beschreibung:
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4245R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4245R-A350
Lokale Artikelnummer::
BOSSBS-4245R-A350
Beschreibung:
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4521R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4521R-HRP
Lokale Artikelnummer::
BOSSBS-4521R-HRP
Beschreibung:
FMDV Polyprotein (VP1 protein)
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8929R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8929R-FITC
Lokale Artikelnummer::
BOSSBS-8929R-FITC
Beschreibung:
Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10498R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10498R-A350
Lokale Artikelnummer::
BOSSBS-10498R-A350
Beschreibung:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7568R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7568R-A750
Lokale Artikelnummer::
BOSSBS-7568R-A750
Beschreibung:
May induce necrosis and apoptosis. May play a role in cell viability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10377R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10377R-A750
Lokale Artikelnummer::
BOSSBS-10377R-A750
Beschreibung:
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterised by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localises to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3294R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3294R-CY7
Lokale Artikelnummer::
BOSSBS-3294R-CY7
Beschreibung:
Protein which catalyzes the phosphorylation of serine or threonine residues on target proteins by using ATP as phosphate donor. Such phosphorylation may cause changes in the function of the target protein. Protein kinases share a conserved catalytic core common to both serine/ threonine and tyrosine protein kinases.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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