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BIOSS INC
Artikel-Nr:
(BOSSBS-10955R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10955R-A680
Lokale Artikelnummer::
BOSSBS-10955R-A680
Beschreibung:
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9906R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9906R-A680
Lokale Artikelnummer::
BOSSBS-9906R-A680
Beschreibung:
CRHBP is a potent stimulator of synthesis and secretion of preopiomelanocortin derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH binding protein which inactivates CRH and which may prevent inappropriate pituitary adrenal stimulation in pregnancy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10178R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10178R-A680
Lokale Artikelnummer::
BOSSBS-10178R-A680
Beschreibung:
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyses the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9717R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9717R-A680
Lokale Artikelnummer::
BOSSBS-9717R-A680
Beschreibung:
Nidogens are highly conserved proteins present in vertebrate and invertebrate basement membranes. Nidogens connect the Laminin and Collagen IV networks and integrate other proteins into the membrane. In mammals, two Nidogen proteins, Nidogen and Nidogen-2, interact at comparable levels with Collagen I, IV and Perlecan, serving to stabilize basement membranes and playing a major role in embryogenesis. The two isoforms have a similar shape, consisting of three globular domains, and co-localize in vessel walls and other basement membrane zones. Nidogen-2 is a cell adhesion protein glycosylated at nitrogen and oxygen sites, and is widely distributed in basement membranes in heart, placenta, bone and, to a lesser extent, in pancreas, kidney and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1172R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1172R-A680
Lokale Artikelnummer::
BOSSBS-1172R-A680
Beschreibung:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1602R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1602R-A647
Lokale Artikelnummer::
BOSSBS-1602R-A647
Beschreibung:
The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localised to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterised to date.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1437R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1437R-CY7
Lokale Artikelnummer::
BOSSBS-1437R-CY7
Beschreibung:
MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1459R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1459R-HRP
Lokale Artikelnummer::
BOSSBS-1459R-HRP
Beschreibung:
Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0276R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0276R-A680
Lokale Artikelnummer::
BOSSBS-0276R-A680
Beschreibung:
Lupus La protein (Sjogren syndrome type B antigen) (SS-B) (La ribonucleoprotein) (La autoantigen) plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs. The phosphorylation sites are at the C-terminal part of the protein. Sera from patients with systemic lupus erythematosus(SLE) often contain that react with the normal cellular La protein as if this antigen was foreign.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0236R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0236R-A680
Lokale Artikelnummer::
BOSSBS-0236R-A680
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1286R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1286R-A680
Lokale Artikelnummer::
BOSSBS-1286R-A680
Beschreibung:
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15042R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15042R-FITC
Lokale Artikelnummer::
BOSSBS-15042R-FITC
Beschreibung:
C1orf181
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15403R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15403R-A647
Lokale Artikelnummer::
BOSSBS-15403R-A647
Beschreibung:
<i>Haemophilus influenza</i> <i>B</i>.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15330R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15330R-FITC
Lokale Artikelnummer::
BOSSBS-15330R-FITC
Beschreibung:
C9orf5 (chromosome 9 open reading frame 5), also known as CG2, is a 911 amino acid multi-pass membrane protein that is widely expressed and exists as four alternatively spliced isoforms. The gene encoding C9orf5 maps to human chromosome 9, which consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15391R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15391R-A350
Lokale Artikelnummer::
BOSSBS-15391R-A350
Beschreibung:
GPR89A is a nearly identical copy of the GPR89B gene (MIM612806).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9367R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9367R-A680
Lokale Artikelnummer::
BOSSBS-9367R-A680
Beschreibung:
In eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways, ubiquitination and degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5). The pUb-R2 subunit, originally identified as S5a, is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, liver, skeletal muscle and pancreas. In addition to normal tissue expression, p44S10 is also expressed in several melanoma cell lines, such as MCF-7, 451Lu and WM164. Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation <i>in vivo</i>.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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