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BIOSS INC
Artikel-Nr:
(BOSSBS-9447R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9447R-A647
Lokale Artikelnummer::
BOSSBS-9447R-A647
Beschreibung:
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13384R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13384R-CY5
Lokale Artikelnummer::
BOSSBS-13384R-CY5
Beschreibung:
Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13090R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13090R-A350
Lokale Artikelnummer::
BOSSBS-13090R-A350
Beschreibung:
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13152R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13152R-HRP
Lokale Artikelnummer::
BOSSBS-13152R-HRP
Beschreibung:
FCHO1 (FCH domain only 1) is an 889 amino acid protein that contains one FCH domain and exists as multiple alternatively spliced isoforms. The gene encoding FCHO1 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13054R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13054R-HRP
Lokale Artikelnummer::
BOSSBS-13054R-HRP
Beschreibung:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12925R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12925R-CY3
Lokale Artikelnummer::
BOSSBS-12925R-CY3
Beschreibung:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11689R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11689R-A555
Lokale Artikelnummer::
BOSSBS-11689R-A555
Beschreibung:
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12545R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12545R-A350
Lokale Artikelnummer::
BOSSBS-12545R-A350
Beschreibung:
ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12275R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12275R-CY5
Lokale Artikelnummer::
BOSSBS-12275R-CY5
Beschreibung:
Phocein is a 225 amino acid protein encoded by the human gene MOBKL3. Phocein belongs to the MOB1/phocein family and is phosphorylated on serine residues. Phocein is a widely expressed, highly conserved intracellular protein. The sequence of Phocein has limited homology to the sigma subunits from Clathrin adaptor complexes and contains an additional stretch bearing a putative SH3-binding domain. Phocein is usually associated with membranes but can be present in the cytosol, where it behaves as a protein complex. Phocein is the major partner of the striatin family members, which are scaffolding proteins involved in signaling and trafficking. Due to its association with Dynamin via direct interactions with nucleotide diphosphate kinase (NDPK) and Eps15, Phocein has been implicated in vesicular trafficking, acting in particular in the endocytic process.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12174R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12174R-A488
Lokale Artikelnummer::
BOSSBS-12174R-A488
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8561R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8561R-CY5
Lokale Artikelnummer::
BOSSBS-8561R-CY5
Beschreibung:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9681R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9681R-HRP
Lokale Artikelnummer::
BOSSBS-9681R-HRP
Beschreibung:
C19orf45 is a 505 amino acid protein that is encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12127R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12127R-FITC
Lokale Artikelnummer::
BOSSBS-12127R-FITC
Beschreibung:
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The three glycoproteins that comprise the voltage-gated sodium channel proteins include a pore-forming Beta subunit, a noncovalently associated Beta 1 subunit and a disulfide-linked Beta 2 subunit. Na+ CP type VII Alpha (Sodium channel protein type 7 subunit alpha), also known as SCN6A, Sodium channel protein cardiac and skeletal muscle subunit alpha and putative voltage-gated sodium channel subunit alpha Nax, is a 1682 amino acid multi-pass membrane protein that belongs to the sodium channel family. Primarily expressed in uterus and heart, Na+ CP type VII Alpha may function in the regulation of salt intake behavior and central sensing of body-fluid sodium levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3058R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3058R-A488
Lokale Artikelnummer::
BOSSBS-3058R-A488
Beschreibung:
Induces apoptosis and anoikis. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13106R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13106R-CY7
Lokale Artikelnummer::
BOSSBS-13106R-CY7
Beschreibung:
Catalyzes the rearrangement of -S-S- bonds in proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6976R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6976R
Lokale Artikelnummer::
BOSSBS-6976R
Beschreibung:
Phospholipase C beta 1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Its gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for its gene.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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