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BIOSS INC
Artikel-Nr:
(BOSSBS-13595R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13595R-CY7
Lokale Artikelnummer::
BOSSBS-13595R-CY7
Beschreibung:
DPPA4 (developmental pluripotency associated 4) is a 304 amino acid protein that localizes to the nucleus and is thought to be involved in the maintenance of cell pluripotentiality during embryogenesis. The gene encoding DPPA4 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1646R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1646R-CY5
Lokale Artikelnummer::
BOSSBS-1646R-CY5
Beschreibung:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0076M)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0076M
Lokale Artikelnummer::
BOSSBS-0076M
Beschreibung:
Anti-APBA1 Mouse Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1152R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1152R
Lokale Artikelnummer::
BOSSBS-1152R
Beschreibung:
Anti-ATP1B2 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11799R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11799R-CY5
Lokale Artikelnummer::
BOSSBS-11799R-CY5
Beschreibung:
TMEM18 is a 140 amino acid multi-pass membrane protein that localizes to the nuclear membrane and is expressed in the brain. TMEM18 functions as a cell migration modulator which enhances the glioma-specific migration ability of neural precursor and neural stem cells.Overexpression of TMEM18 increases migration of human and murine neural stem cells, whereas knockdown of TMEM18 mRNA reduces cellular migration. Two specific single nucleotide polymorphisms (SNPs) within the TMEM18 gene locus known as rs6548238 and rs756131 have been linked to obesity susceptibility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11872R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11872R-CY5
Lokale Artikelnummer::
BOSSBS-11872R-CY5
Beschreibung:
Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses. Velis contain the PDZ motif involved in recruiting cell adhesion molecules, receptors, and channels. Veli1 (also designated Lin-7A and MALS-1), Veli2 (also designated Lin-7B and MALS-2), and Veli3 (also designated Lin-7C and MALS-3) are mammalian homologs of C. elegans LIN-7. Veli proteins are ubiquitously expressed with high expression in brain, liver, and testis. Velis are localized at the synaptic junctions in neurons. Velis bind to CASK, a neurexin-binding protein highly concentrated in synapses, and Mint1, a binding partner with a vesicle trafficking protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11085R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11085R
Lokale Artikelnummer::
BOSSBS-11085R
Beschreibung:
Anti-PCDH7 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1020R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1020R
Lokale Artikelnummer::
BOSSBS-1020R
Beschreibung:
Anti-MAPK3 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7997R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7997R-CY7
Lokale Artikelnummer::
BOSSBS-7997R-CY7
Beschreibung:
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7545R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7545R-HRP
Lokale Artikelnummer::
BOSSBS-7545R-HRP
Beschreibung:
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11066R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11066R-HRP
Lokale Artikelnummer::
BOSSBS-11066R-HRP
Beschreibung:
The downstream of kinase family (Dok-1-7) are members of a class of “docking†proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6213R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6213R-CY3
Lokale Artikelnummer::
BOSSBS-6213R-CY3
Beschreibung:
This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7826R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7826R-A647
Lokale Artikelnummer::
BOSSBS-7826R-A647
Beschreibung:
May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6575R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6575R-CY5.5
Lokale Artikelnummer::
BOSSBS-6575R-CY5.5
Beschreibung:
Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6406R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6406R-CY5
Lokale Artikelnummer::
BOSSBS-6406R-CY5
Beschreibung:
CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6916R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6916R-A488
Lokale Artikelnummer::
BOSSBS-6916R-A488
Beschreibung:
Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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