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BIOSS INC
Artikel-Nr:
(BOSSBS-1891R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1891R
Lokale Artikelnummer::
BOSSBS-1891R
Beschreibung:
May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13073R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13073R
Lokale Artikelnummer::
BOSSBS-13073R
Beschreibung:
eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15479R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15479R
Lokale Artikelnummer::
BOSSBS-15479R
Beschreibung:
Anti-HHLA3 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6058R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6058R-CY3
Lokale Artikelnummer::
BOSSBS-6058R-CY3
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9781R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9781R-A680
Lokale Artikelnummer::
BOSSBS-9781R-A680
Beschreibung:
Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12043R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12043R-CY3
Lokale Artikelnummer::
BOSSBS-12043R-CY3
Beschreibung:
Members of the paired homeobox family play a role in regulating cell development and pattern formation during embryonic stages. UNCX (UNC homeobox), also known as UNCX4.1, is a 531 amino acid nuclear transcription factor involved in neurogenesis and somitogenesis. Containing one homeobox DNA-binding domain, UNCX belongs to the paired homeobox family and UNC4 subfamily. UNCX assists in the formation of connections between hypothalamic neurons and the pituitary, which is necessary for central neurons to deliver hormones into peripheral blood. UNCX also plays a role in maintaining differentiation of the axial skeleton and acts upstream of Pax-9. The gene encoding UNCX maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8389R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8389R-A680
Lokale Artikelnummer::
BOSSBS-8389R-A680
Beschreibung:
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0647R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0647R-CY5
Lokale Artikelnummer::
BOSSBS-0647R-CY5
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12933R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12933R-CY3
Lokale Artikelnummer::
BOSSBS-12933R-CY3
Beschreibung:
Chymotrypsins are digestive enzymes that can perform proteolysis by cleaving peptides at the carboxyl side of tyrosine, tryptophan, leucine and phenylalanine, although over time they can also hydrolyze other amide bonds, especially those with leucine-donated carboxyls. Chymotrypsins cleave peptide bonds by attacking the non-reactive carbonyl group with a powerful nucleophile, which momentarily becomes covalently bonded to the substrate to form an intermediate. Chymotrypsin B (CTRB1) and Chymotrypsin B2 (CTRB2) are synthesized in the pancreas by protein biosynthesis as precursors that are enzymatically inactive, but become active as three polypeptide molecules that are interconnected by disulfide bonds.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10280R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10280R-A680
Lokale Artikelnummer::
BOSSBS-10280R-A680
Beschreibung:
Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1231R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1231R-CY3
Lokale Artikelnummer::
BOSSBS-1231R-CY3
Beschreibung:
Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0301R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0301R
Lokale Artikelnummer::
BOSSBS-0301R
Beschreibung:
Anti-DNMT3B Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15520R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15520R-A350
Lokale Artikelnummer::
BOSSBS-15520R-A350
Beschreibung:
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9830R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9830R-A750
Lokale Artikelnummer::
BOSSBS-9830R-A750
Beschreibung:
C3orf39, also known as AGO61, is a 580 amino acid secreted protein belonging to the glycosyltransferase 61 family. C3orf39 is encoded by a gene that maps to human chromosome 3p25.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumour suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11645R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11645R-HRP
Lokale Artikelnummer::
BOSSBS-11645R-HRP
Beschreibung:
Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9614R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9614R-A350
Lokale Artikelnummer::
BOSSBS-9614R-A350
Beschreibung:
Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf140 gene product has been provisionally designated C14orf140 pending further characterization.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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