BIOSENSIS PTY
Artikel-Nr:
(BSENC-1393-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
C-1393-50
Lokale Artikelnummer::
BSENC-1393-50
Beschreibung:
Neurofilaments are composed of three intermediate filament proteins: light (~68 kDa), medium (~160 kDa) and heavy (~200 kDa), which are involved in the maintenance of the neuronal caliber. Neurofilament medium runs on SDS-PAGE gels in the range 145-170 kDa, with some variation in different species.
VE:
1 * 50 µl
Artikel-Nr:
(BSENR-1751-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1751-50
Lokale Artikelnummer::
BSENR-1751-50
Beschreibung:
This antibody is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling.
VE:
1 * 50 µG
Artikel-Nr:
(BSENM-1378-250)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1378-250
Lokale Artikelnummer::
BSENM-1378-250
Beschreibung:
Neurofilaments can be defined as the intermediate or 10nm diameter filaments found in neuronal cells. They are composed a mixture of subunits which often includes the neurofilament triplet proteins, NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Alpha-internexin is a ~66 kDa Class IV intermediate filament subunit expressed in large amounts early in neuronal development, but is downregulated in many neurons as development procedes. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to alpha-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of alpha-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage.
VE:
1 * 250 µl
Artikel-Nr:
(BSENR-165-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-165-100
Lokale Artikelnummer::
BSENR-165-100
Beschreibung:
Clathrin is a major protein component of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice to either the plasma membrane or the trans-Golgi network. These specialised organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. Clathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat. In the presence of light chains, hub assembly is influenced by both the pH and the concentration of calcium. Clathrin localises to the cytoplasmic face of coated pit and vesicle membranes.
VE:
1 * 100 µl
Artikel-Nr:
(BSENS-1759-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-1759-100
Lokale Artikelnummer::
BSENS-1759-100
Beschreibung:
Sheep serum was obtained from non-immunised animals. This whole serum can be used as negative control antibody for various immunological techniques where sheep primary antibodies (whole serum) are used.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-1491-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1491-50
Lokale Artikelnummer::
BSENR-1491-50
Beschreibung:
Adrenocorticotropic hormone (ACTH) is cleaved from the precursor pro-opiomelanocortin (POMC). The hormone is produced and secreted by the pituitary gland and stimulates release of cortisol by adrenal glands.
VE:
1 * 50 µG
Artikel-Nr:
(BSENR-1319-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1319-100
Lokale Artikelnummer::
BSENR-1319-100
Beschreibung:
The Myc tag contains the amino acids Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu (E-Q-K-L-I-S-E-E-D-L) corresponding to amino acids 410-419 of human Myc. This tag is widely used for monitoring expression of recombinant proteins in bacteria, insect and mammalian cells.
VE:
1 * 100 µG
Artikel-Nr:
(BSENS-071-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-071-100
Lokale Artikelnummer::
BSENS-071-100
Beschreibung:
C-reactive protein has several roles associated with host defence such as; promoting agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. COFACTOR: Binds 2 calcium ions per subunit. C-reactive protein exists as a homopentamer. Pentaxin (or Pentraxin) have a discoid arrangement of 5 non-covalently bound subunits. There are 2 alternatively spliced isoforms. C-reactive protein is found in plasma and its concentration increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.
VE:
1 * 100 µl
Artikel-Nr:
(BSENC-1538-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
C-1538-100
Lokale Artikelnummer::
BSENC-1538-100
Beschreibung:
Peptide YY (PYY) is secreted from endocrine cells in the lower small intestine, colon and pancreas. PYY inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility (Ref: SWISS-Prot).
VE:
1 * 100 µl
Artikel-Nr:
(BSENM-1702-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1702-100
Lokale Artikelnummer::
BSENM-1702-100
Beschreibung:
High-mobility group proteins were named originally since they are abundand relatively low molecular weight proteins which run quickly on SDS-PAGE gels. High-mobility group protein box 1 (HMGB1, Amphoterin) is one of these. The "bx" in the name refers to the so-called high mobility group (HMG) box, a compact domain involved in DNA binding and protein-protein interactions. the HMGB1 molecule has two of these HMG domains. The protein is alslo called amphoterin, this name being derived from the presence of two highly charged regions in the molecule, a relatively neutrally charged N-terminus and a very negatively charged C-terminus. In fact the molecule is very unusually charged throughout, the human sequence consisting of 16.7% Glutamic acid, 9.3% Aspartic acid, 20% lysine and 9.3% Arginine. HMGB1 can bind Toll like receptor 4 (TLR4) and the Receptor for Advanced Glycation End products (RAGE). TLRs are components of the innate immune system, first recognized as a family of receptors which recognize "Pathogen Associated Molecular Pattern molecules (PAMPs). PAMPs are common components of bacteria and when TLRs bind these a strong inflammatory response is activated. More recently it has been recognized that TLRs can also be activated by Damage Associated Molecular Pattern molecules (DAMPs), which are endogenous substances released from damaged and diseased cells which also bind to TLR family receptors and also activate inflammation. HMGB1 is such a DAMP, binding to TLR4, and much evidence suggests that HMGB1 is a strong activator of inflammation. Interestingly, HMGB1 is released by necrotic cells but not by apoptotic cells (1).
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-1494-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1494-50
Lokale Artikelnummer::
BSENR-1494-50
Beschreibung:
Endomorphins 1 and 2 are endogenous opioid peptides which have the highest affinity for the mu-opioid receptors. Located in various parts of the brain and interacts with mu-opioid receptors and produces analgesia.
VE:
1 * 50 µG
Artikel-Nr:
(BSENM-1725-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1725-100
Lokale Artikelnummer::
BSENM-1725-100
Beschreibung:
MAP1A and MAP1B are microtubule-associated protein which mediate the physical interactions between microtubules and components of the cytoskeleton (probably involved in autophagosome formation). MAP1A and MAP1B each consist of a heavy chain subunit and 3 different light chain subunits (LC1, LC2 and LC3). MAP1LC3A is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor form of MAP1LC3A is cleaved by APG4/ATG4B to form the cytosolic form LC3-1. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. MAP1LC3A is most abundant in heart, brain, liver, skeletal muscle and testis but is absent in thymus and peripheral leukocytes.
VE:
1 * 100 µG
Artikel-Nr:
(BSENGP-031-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
GP-031-50
Lokale Artikelnummer::
BSENGP-031-50
Beschreibung:
Proopiomelanocortin (POMC) is the precursor of the melanocortin peptides alpha, beta and gamma. POMC neurons in the arcuate nucleus of the hypothalamus function as key central regulators of food intake and homeostatic control of energy balance in both rodents and non-human primates.
VE:
1 * 50 µl
Artikel-Nr:
(BSENC-1798-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
C-1798-50
Lokale Artikelnummer::
BSENC-1798-50
Beschreibung:
Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Ref: uniprot.org. Antibody is specific for calbindin and does not recognize closely related proteins parvalbumin and calretinin as determined by Western Blotting.
VE:
1 * 50 µl
Artikel-Nr:
(BSENM-1778-50-B)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1778-50-B
Lokale Artikelnummer::
BSENM-1778-50-B
Beschreibung:
Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released.
Biosensis' biotinylated proNGF antibody allowing more flexibility in experimental design by using the biotin-avidin/streptavidin detection method. The ability of biotinylated proNGF antibody to detect proNGF has been validated by WB.
VE:
1 * 50 µG
Artikel-Nr:
(BSENBL-004-500)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
BL-004-500
Lokale Artikelnummer::
BSENBL-004-500
Beschreibung:
HETEROPHILIC ANTIBODY BLOCKER ELISAKIT 1 * 500 G
VE:
1 * 500 µG
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||